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即时自旋交叉配血用于检测ABO血型不相容性时的局限性。

Limitations of the immediate spin crossmatch when used for detecting ABO incompatibility.

作者信息

Berry-Dortch S, Woodside C H, Boral L I

出版信息

Transfusion. 1985 Mar-Apr;25(2):176-8. doi: 10.1046/j.1537-2995.1985.25285169217.x.

DOI:10.1046/j.1537-2995.1985.25285169217.x
PMID:3984013
Abstract

In the eleventh edition of the AABB's Standards for Blood Banks and Transfusion Services the requirement for an antiglobulin crossmatch was deleted if no clinically significant unexpected antibodies are detected in recipient serum testing and if there is no history of detection of such antibodies. Test methods that demonstrate ABO incompatibility remain a requirement; however, the means to accomplish this may prove controversial. The immediate spin crossmatch has been used for the purpose of detecting ABO incompatibility by many workers. Nonetheless, limitations of this technique became apparent in tests between A2B donor red cells and group B patient sera. The results of 204 of 531 immediate spin crossmatches, between these two blood groups, were found to be negative.

摘要

在美国血库协会(AABB)的《血库与输血服务标准》第十一版中,如果在受血者血清检测中未检测到具有临床意义的意外抗体,且没有此类抗体的检测史,则抗球蛋白交叉配血的要求被删除。证明ABO血型不相容的检测方法仍然是一项要求;然而,实现这一目的的手段可能存在争议。许多工作人员一直使用立即离心交叉配血来检测ABO血型不相容性。尽管如此,该技术的局限性在A2B供者红细胞与B型患者血清之间的检测中变得明显。在这两个血型之间进行的531次立即离心交叉配血中,有204次结果为阴性。

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