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资源有限环境下医源性输尿管阴道瘘的管理:乌干达四个瘘管手术中心的12年经验

The Management of Iatrogenic Ureterovaginal Fistula in a Resource-Limited Setting: A 12-Year Experience at Four Fistula Surgery Centers in Uganda.

作者信息

Kajabwangu Rogers, Geissbüehler Verena, Tibaijuka Leevan, Byamukama Onesmus, Kalyebara Paul K, Ainomugisha Brenda, Margolis Thomas, Lukabwe Henry, Njagi Joseph, Lugobe Henry M, Kayondo Musa

机构信息

Obstetrics and Gynecology, Mbarara University of Science and Technology, Mbarara, UGA.

Obstetrics and Gynecology, University of Basel, Geneva, CHE.

出版信息

Cureus. 2024 Dec 21;16(12):e76170. doi: 10.7759/cureus.76170. eCollection 2024 Dec.

Abstract

Background Ureterovaginal fistulae usually follow iatrogenic injury to the ureter during pelvic surgery. This manifests as urine incontinence and results in serious psychosocial effects on women. Ureterovaginal fistulae unlike vesicovaginal fistulae present challenges in diagnosis and management especially in resource-constrained settings. Objective The objective of this study is to describe the magnitude, etiology, diagnosis, management, and outcomes of iatrogenic ureterovaginal fistula in Uganda over a 12-year period. Methods A retrospective review of charts for women who had fistula repair at four fistula repair centers in Uganda from 2010 to 2021 was conducted. The diagnosis of ureterovaginal fistula was made clinically using a history of leakage of urine through the vagina following a pelvic surgery, a negative methylene blue dye test, and a three-swab test. All women were managed using open transvesical ureteral reimplantation with or without a Boari flap. The outcome of surgery was successful fistula repair with urine continence and was determined at two months post-surgery. Results Overall, 477 women were managed for genitourinary fistulae during the study period. Approximately one in every 10 women with genitourinary fistula had an iatrogenic ureterovaginal fistula (n=47, 9.8%). The mean age of women with ureterovaginal fistula was 31.9 (SD: ±11.8) years. The majority of ureterovaginal fistulae (n=33, 70.7%) followed cesarean sections done at general hospitals (n=22, 46.8%) by medical officers (n=32, 68.1%). Clinical assessment was accurate in diagnosing ureterovaginal fistula. Successful fistula repair was achieved in 45 (95.7%) cases. Conclusion Iatrogenic ureterovaginal fistulae are common in Uganda, and most follow cesarean section performed at lower-level health facilities by medical officers. In resource-limited settings where advanced diagnostic techniques are not available or not affordable, simple stepwise clinical evaluation is effective in making a diagnosis. Open ureteral reimplantation with or without a Boari flap has a high successful repair rate.

摘要

背景 输尿管阴道瘘通常继发于盆腔手术中输尿管的医源性损伤。这表现为尿失禁,并对女性造成严重的心理社会影响。与膀胱阴道瘘不同,输尿管阴道瘘在诊断和治疗方面存在挑战,尤其是在资源有限的环境中。目的 本研究的目的是描述乌干达12年间医源性输尿管阴道瘘的发生率、病因、诊断、治疗及结果。方法 对2010年至2021年在乌干达四个瘘管修复中心接受瘘管修复的女性患者病历进行回顾性研究。输尿管阴道瘘的诊断通过盆腔手术后经阴道漏尿史、亚甲蓝染料试验阴性及三拭子试验进行临床诊断。所有女性均采用开放经膀胱输尿管再植术,可选择或不采用Boari瓣。手术结果为瘘管成功修复且恢复控尿,于术后两个月确定。结果 总体而言,在研究期间有477名女性接受了泌尿生殖瘘的治疗。每10名泌尿生殖瘘女性中约有1例为医源性输尿管阴道瘘(n = 4

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b00a/11747545/964b568d6d6c/cureus-0016-00000076170-i01.jpg

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