Polak Dagna, Korkosz Mariusz, Guła Zofia
Department of Rheumatology, Immunology and Internal Medicine, University Hospital in Kraków, Kraków, Poland.
Department of Rheumatology and Immunology, Jagiellonian University Medical College, Kraków, Poland.
Rheumatol Int. 2025 Jan 22;45(2):36. doi: 10.1007/s00296-024-05780-5.
Sleep disorders are relatively common among patients with inflammatory arthritis (IA) and have a substantial impact on their quality of life. Although patients frequently recognize poor sleep as an important component of their disease, dyssomnias remain often underdiagnosed and untreated in routine clinical practice. This narrative review examines the prevalence, mechanism, risk factors and management of dyssomnias in rheumatoid arthritis (RA), axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). Relevant articles were retrieved from PUBMED, Scopus and DOAJ. The pathomechanism of sleep disorders in IA is multifactorial and partially differs in RA, axSpA and PsA, however, comparative studies are lacking. Various factors affecting sleep quality, including disease activity, pain, mood disorders, fatigue and female gender, have been examined, but their interplay complicates establishing clear causal relationships. The bidirectional link between sleep quality and rheumatic disease activity highlights the complexity of this issue and demonstrates the importance of holistic management of rheumatic patients. Both pharmacological (e.g., hypnotics, NSAIDs, antidepressants, cannabidiol) and non-pharmacological (e.g., psychotherapy, physical activity) interventions for improving sleep were analyzed. Additionally, questionnaires currently used for assessing sleep were discussed. This review aims to provide a comprehensive overview of sleep disorders across the three most common types of IA, emphasizing the need to develop reliable and patient-friendly tools for everyday clinical practice and further comparative research.
睡眠障碍在炎症性关节炎(IA)患者中相对常见,对他们的生活质量有重大影响。尽管患者经常认识到睡眠不佳是其疾病的一个重要组成部分,但在常规临床实践中,睡眠障碍往往仍未得到充分诊断和治疗。这篇叙述性综述探讨了类风湿关节炎(RA)、轴性脊柱关节炎(axSpA)和银屑病关节炎(PsA)中睡眠障碍的患病率、机制、危险因素及管理。从PUBMED、Scopus和DOAJ检索了相关文章。IA中睡眠障碍的发病机制是多因素的,在RA、axSpA和PsA中部分有所不同,然而,缺乏比较研究。已经研究了各种影响睡眠质量的因素,包括疾病活动度、疼痛、情绪障碍、疲劳和女性性别,但它们之间的相互作用使得建立明确的因果关系变得复杂。睡眠质量与风湿性疾病活动度之间的双向联系凸显了这个问题的复杂性,并证明了对风湿性疾病患者进行整体管理的重要性。分析了用于改善睡眠的药物(如催眠药、非甾体抗炎药、抗抑郁药、大麻二酚)和非药物(如心理治疗、体育活动)干预措施。此外,还讨论了目前用于评估睡眠的问卷。这篇综述旨在全面概述三种最常见类型的IA中的睡眠障碍,强调需要开发适用于日常临床实践的可靠且患者友好的工具以及进一步的比较研究。