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肾上腺肿瘤评估及偶发瘤患者代谢谱分析。

Evaluation of adrenal tumors and analysis of the metabolic profile of patients with incidentaloma.

作者信息

Montalvão Pedro Victor Gonçalves, Mangueira Iuri Moura, Alves Gabriel DA Motta, Cordeiro João Vitor Fazzio, Costa Marcia Helena Soares, Ravanini Guilherme DE Andrade Gagheggi

机构信息

- Universidade Federal do Estado do Rio de Janeiro, Medicina - Rio de Janeiro - RJ - Brasil.

- Universidade Estadual do Rio de Janeiro, Serviço de Clínica Médica - Rio de Janeiro - RJ - Brasil.

出版信息

Rev Col Bras Cir. 2025 Jan 17;51:e20243685. doi: 10.1590/0100-6991e-20243685-en. eCollection 2025.

DOI:10.1590/0100-6991e-20243685-en
PMID:39841720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11702972/
Abstract

INTRODUCTION

Advances in imaging methods have led to an increasingly frequent diagnosis of adrenal gland lesions as incidental findings. Despite progress in this field, there is still limited information regarding the epidemiology of the clinical and metabolic profile of patients with adrenal incidentaloma (AI). The objective is analyze the epidemiology of adrenal tumors at Gaffrée e Guinle University Hospital (HUGG) and compare it with data from the literature.

METHOD

This is a cross-sectional study that included patients of any gender and age who was treated at HUGG for adrenal tumors.

RESULTS

The following variables were evaluated: age, gender, functionality, benignity, and size. We also analyzed the metabolic profile of patients with AI, specifically those with mild autonomy cortisol secretion. Out of 31 patients with adrenal tumors, 68% were female. The mean age was 55 years with a standard deviation of ±16.2. 54% of the sample had adrenal incidentalomas. 93.6% of the sample had benign cases. Among the adrenal incidentalomas, 53% were non-functioning. In patients with adrenal tumors, only 10% had metabolic syndrome, while in patients with mild autonomous cortisol secretion, this number rose to 17%.

CONCLUSION

The sample of patients with adrenal tumors and incidentaloma at HUGG presented a prevalence of metabolic complications similar to that found in the literature.

摘要

引言

成像方法的进步使得肾上腺病变作为偶然发现的诊断越来越频繁。尽管该领域取得了进展,但关于肾上腺偶发瘤(AI)患者的临床和代谢特征的流行病学信息仍然有限。目的是分析加夫雷和吉恩勒大学医院(HUGG)肾上腺肿瘤的流行病学,并将其与文献数据进行比较。

方法

这是一项横断面研究,纳入了在HUGG接受肾上腺肿瘤治疗的任何性别和年龄的患者。

结果

评估了以下变量:年龄、性别、功能、良性和大小。我们还分析了AI患者的代谢特征,特别是那些轻度自主性皮质醇分泌的患者。在31例肾上腺肿瘤患者中,68%为女性。平均年龄为55岁,标准差为±16.2。54%的样本患有肾上腺偶发瘤。93.6%的样本为良性病例。在肾上腺偶发瘤中,53%无功能。在肾上腺肿瘤患者中,只有10%患有代谢综合征,而在轻度自主性皮质醇分泌的患者中,这一数字上升至17%。

结论

HUGG肾上腺肿瘤和偶发瘤患者样本中代谢并发症的患病率与文献中发现的相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/a22757472216/rcbc-51-e20243685-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/1825774f8aa6/rcbc-51-e20243685-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/a6856562f9f0/rcbc-51-e20243685-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/5163effa9d01/rcbc-51-e20243685-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/e5291f3a2ddd/rcbc-51-e20243685-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/2dbae0187c2d/rcbc-51-e20243685-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/a22757472216/rcbc-51-e20243685-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/1825774f8aa6/rcbc-51-e20243685-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/a6856562f9f0/rcbc-51-e20243685-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/5163effa9d01/rcbc-51-e20243685-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/e5291f3a2ddd/rcbc-51-e20243685-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/2dbae0187c2d/rcbc-51-e20243685-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cc7/11702972/a22757472216/rcbc-51-e20243685-g006.jpg

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