Gross Angelina S, Raffeiner Margot, Zeng Yonglun, Üstün Suayib, Dagdas Yasin
Gregor Mendel Institute of Molecular Plant Biology, Vienna, Austria; email:
Current affiliation: Department of Applied Genetics and Cell Biology, Institute of Molecular Plant Biology, BOKU University of Natural Resources and Life Sciences, Vienna, Austria.
Annu Rev Plant Biol. 2025 May;76(1):197-227. doi: 10.1146/annurev-arplant-060324-094912. Epub 2025 Jan 22.
Autophagy has emerged as an essential quality control pathway in plants that selectively and rapidly removes damaged or unwanted cellular components to maintain cellular homeostasis. It can recycle a broad range of cargoes, including entire organelles, protein aggregates, and even invading microbes. It involves the de novo biogenesis of a new cellular compartment, making it intimately linked to endomembrane trafficking pathways. Autophagy is induced by a wide range of biotic and abiotic stress factors, and autophagy mutant plants are highly sensitive to stress, making it an attractive target for improving plant stress resilience. Here, we critically discuss recent discoveries related to plant autophagy and highlight open questions and future research areas.
自噬已成为植物中一种重要的质量控制途径，它能选择性且快速地清除受损或不需要的细胞成分，以维持细胞内稳态。它可以回收种类广泛的货物，包括整个细胞器、蛋白质聚集体，甚至是入侵的微生物。它涉及一个新的细胞区室的从头生物发生，使其与内膜运输途径密切相关。自噬由多种生物和非生物胁迫因素诱导，自噬突变体植物对胁迫高度敏感，这使其成为提高植物胁迫恢复力的一个有吸引力的靶点。在这里，我们批判性地讨论了与植物自噬相关的最新发现，并突出了悬而未决的问题和未来的研究领域。
