Lau H L, Lawrence K W, King T M
Int J Gynaecol Obstet. 1978;17(1):68-72. doi: 10.1002/j.1879-3479.1979.tb00118.x.
Further evaluation of the nonrefrigerated capillary tube pregnancy test is presented. A 127-mm by 2-mm glass capillary tube containing lyophilized antibody to human chorionic gonadotropin and latex indicator particles is used. Urine is drawn into the tube by capillary action; then, the tube is tilted to allow the urine to dissolve the antibody and to suspend the latex particles. The test results are read after a one-hour incubation period. Test results were evaluated against histopathologic and clinical data. Special efforts were made to stress the false-positive rate of the test by tripling the number of negative cases and doubling the sample size. A 99.82% agreement, a 0.18% false-negative rate and a 0% false-positive rate were obtained. In 52 confirmed pregnancies, the more sensitive capillary test detected human chorionic gonadotropin, whereas the commercial tests did not. Human chorionic gonadotropin was also detected one week earlier than reported in the first series.
本文介绍了对非冷藏毛细管妊娠试验的进一步评估。使用一根127毫米长、2毫米宽的玻璃毛细管，其中含有冻干的人绒毛膜促性腺激素抗体和乳胶指示颗粒。尿液通过毛细作用被吸入管中；然后，将管子倾斜以使尿液溶解抗体并悬浮乳胶颗粒。孵育一小时后读取测试结果。根据组织病理学和临床数据对测试结果进行评估。通过将阴性病例数量增加两倍和样本量增加一倍，特别强调了该测试的假阳性率。得到了99.82%的一致性、0.18%的假阴性率和0%的假阳性率。在52例确诊妊娠中，更灵敏的毛细管试验检测到了人绒毛膜促性腺激素，而商业试验则未检测到。人绒毛膜促性腺激素的检测时间也比第一系列报道的时间早一周。
