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编织型EndoBridge与支架辅助弹簧圈栓塞治疗急性破裂宽颈分叉动脉瘤的比较:单中心经验

Comparison of Woven EndoBridge and stent-assisted coiling for treatment of acutely ruptured wide-neck bifurcation aneurysms: Single-center experience.

作者信息

Ghanaati Hossein, Rahmatian Aryoobarzan, Torkaman Amir, Dashtkoohi Mohammad, Ohadi Mohammad Amin Dabbagh

机构信息

Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Emam-Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Department of Neurology, Ilam University of Medical Sciences, Ilam, Iran.

出版信息

J Cerebrovasc Endovasc Neurosurg. 2025 Mar;27(1):33-39. doi: 10.7461/jcen.2024.E2024.11.002. Epub 2025 Jan 24.

Abstract

OBJECTIVE

Treating wide-necked bifurcation aneurysms (WNBA) is challenging. Nevertheless, recent progress in endovascular techniques is promising. Woven EndoBridge devices (WEB) have exhibited outcomes comparable to conventional treatments like stent-assisted coiling (SAC) in treating aneurysms. However, their safety and efficacy in managing acutely ruptured aneurysms remain a topic of interest. This study focuses on this issue.

METHODS

We searched our database from 2020 to 2023 and found 38 patients with acutely (< a week) ruptured WNBA. We extracted radiologic and clinical data from the available medical reports. Favorable functional and radiologic outcomes were assessed using the modified Rankin scale (mRS) and modified Raymond-Roy occlusion classification (MRRC).

RESULTS

Our study population comprised 15 aneurysms treated with WEB and 25 treated with SAC. Operational time was significantly lower in the WEB compared to the SAC group (39.3 vs 66.2 minutes, p value: < 0.001). Immediate (p value=0.64) and the 18th-month (p value=0.42) occlusion rates were comparable between the two groups. Favorable mRS scores in the 3rd month were seen in 100% of SAC patients and 93.3% of WEB patients (p value=0.79). Retreatment (p value=1.0) and complication (p value=0.39) rates were comparable. Vasospasms after the procedure were the most common complication.

CONCLUSIONS

WEB demonstrated comparable safety and efficacy to SAC in patients with acutely ruptured WNBA. Notably, WEB had a shorter procedure duration. Additional studies with extended follow-up periods are necessary for comprehensive evaluation.

摘要

目的

治疗宽颈分叉动脉瘤(WNBA)具有挑战性。然而,血管内技术的最新进展很有前景。编织型血管内桥接装置(WEB)在治疗动脉瘤方面已展现出与支架辅助弹簧圈栓塞术(SAC)等传统治疗方法相当的效果。然而,其在治疗急性破裂动脉瘤方面的安全性和有效性仍是一个受关注的话题。本研究聚焦于这个问题。

方法

我们检索了2020年至2023年的数据库,发现38例急性(<1周)破裂的WNBA患者。我们从现有的医学报告中提取了放射学和临床数据。使用改良Rankin量表(mRS)和改良Raymond-Roy闭塞分级(MRRC)评估良好的功能和放射学结果。

结果

我们的研究人群包括15例接受WEB治疗的动脉瘤和25例接受SAC治疗的动脉瘤。与SAC组相比,WEB组的手术时间显著更短(39.3分钟对66.2分钟,p值:<0.001)。两组之间的即刻(p值 = 0.64)和第18个月(p值 = 0.42)闭塞率相当。在第3个月时,100%的SAC患者和93.3%的WEB患者获得了良好的mRS评分(p值 = 0.79)。再次治疗率(p值 = 1.0)和并发症发生率(p值 = 0.39)相当。术后血管痉挛是最常见的并发症。

结论

在急性破裂的WNBA患者中,WEB显示出与SAC相当的安全性和有效性。值得注意的是,WEB的手术持续时间更短。需要进行更长随访期的进一步研究以进行全面评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a6/11984267/815ced81a43e/jcen-2024-e2024-11-002f1.jpg

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