Cai Peter Y, Balthazar Andrea, Tham Regina L, Omar Badar, Mauskar Sangeeta, Wickremasinghe Walter, Cilento Bartley G Jr, Nelson Caleb P
Department of Urology, Boston Children's Hospital, 300 Longwood Avenue, Hunnewell 3, Boston, MA 02115.
Complex Care Service, Division of General Pediatrics, Boston Children's Hospital, 300 Longwood Avenue, Hunnewell Ground Floor, Boston, MA 02115.
Urology. 2025 Apr;198:125-129. doi: 10.1016/j.urology.2025.01.031. Epub 2025 Jan 20.
To test the feasibility and efficacy of using an enuresis alarm to guide the timing of post-void residual (PVR) measurement in two different cohorts of non-verbal, non-toilet trained pediatric patients.
We prospectively enrolled 15 infants (Group 1) and 15 medically-complex patients (Group 2) to undergo an 8-hour study period that included a 4-hour intervention period with alarm (PVR after alarm trigger) and a 4-hour control period of routine care (PVR when nurses observe wet diapers). The primary endpoint of PVR volume was analyzed using linear regression with volume as the dependent variable and both study period and patient weight as independent variables. Secondary endpoint of the number of detected voids was analyzed using Mann-Whitney U test.
In Group 1, the median number of voids detected was significantly greater in the alarm versus routine care periods (3 vs 2, P = .0029). Use of alarm was associated with a non-significant mean decrease of 2.23 mL (95% CI -7.09 to 2.63, P = .363) in PVR volume for infants. In Group 2, the median number of detected voids were also significantly different in the alarm versus routine care periods (3 vs 1, P = .0312). Use of alarm was associated with a mean decrease of 21.09 mL (95% CI -40.60 to -1.58, P = .035) in PVR volume.
An enuresis alarm facilitated detecting significantly more voids in both infants and medically-complex, non-verbal children and was also associated with a decrease in PVR volume in the latter group. Such use of enuresis alarms may prove useful to measure PVR more accurately in these challenging populations.
在两组无法用言语表达、未接受如厕训练的儿科患者中，测试使用遗尿报警器指导排尿后残余尿量（PVR）测量时间的可行性和有效性。
我们前瞻性纳入了15名婴儿（第1组）和15名病情复杂的患者（第2组），进行为期8小时的研究，其中包括4小时的报警器干预期（报警器触发后的PVR）和4小时的常规护理对照期（护士观察到尿布潮湿时的PVR）。以尿量为因变量、研究期和患者体重为自变量，采用线性回归分析PVR体积的主要终点。使用Mann-Whitney U检验分析检测到的排尿次数这一次要终点。
在第1组中，报警器期检测到的排尿中位数显著多于常规护理期（3次对2次，P = 0.0029）。对于婴儿，使用报警器与PVR体积平均非显著性降低2.23 mL（95%CI -7.09至2.63，P = 0.363）相关。在第2组中，报警器期和常规护理期检测到的排尿中位数也有显著差异（3次对1次，P = 0.0312）。使用报警器与PVR体积平均降低21.09 mL（95%CI -40.60至-1.58，P = 0.035）相关。
遗尿报警器有助于在婴儿以及病情复杂、无法用言语表达的儿童中检测到更多的排尿次数，并且与后一组的PVR体积减小相关。在这些具有挑战性的人群中，这种使用遗尿报警器的方法可能有助于更准确地测量PVR。
