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用于治疗伴有安德森病变和特发性脊髓疝双重并发症的强直性脊柱炎的远侧椎弓根截骨术:1例罕见病例报告

Distal Pedicle Subtraction Osteotomy for Ankylosing Spondylitis With the Dual Complications of Andersson Lesions and Idiopathic Spinal Cord Hernia: A Rare Case Report.

作者信息

Li Junyu, Yang Zexi, Zhang Xinyu, Shang Zesen, Wu Hongyu, Zheng Danfeng, Sun Zhuoran, Wang Yongqiang, Zeng Yan, Li Weishi, Yu Miao

机构信息

Orthopedic Department, Peking University Third Hospital, Beijing, China.

Beijing Key Laboratory of Spinal Disease Research, Beijing, China.

出版信息

Orthop Surg. 2025 Mar;17(3):971-978. doi: 10.1111/os.14344. Epub 2025 Jan 22.

Abstract

BACKGROUND AND IMPORTANCE

Ankylosing spondylitis (AS) is a systemic chronic inflammatory disease. Andersson lesion (AL) is a late complication of advanced AS. Idiopathic spinal cord hernia (ISCH) is a rare disorder of the spinal cord. However, according to our literature review, the simultaneous occurrence of AL together with ISCH in a single AS patient had never been reported.

CLINICAL PRESENTATION

A 49-year-old male reported a 30-year history of thoracolumbar pain and limited mobility and was diagnosed with AS with dual complications of AL and ICSH. Before correction surgery, physical examination, x-ray, CT, MRI and Blood HLA-B27 examination were performed and a series of radiological parameters, including the degree of kyphosis and the T1-pelvic angle (TPA), were measured. Several days after surgery (Distal PSO was used), we performed examinations to check the patient's physical condition which showed the patient recovered remarkably. CTA was done, indicating that the patient's aorta moved anteriorly with the osteotomy side undamaged. A series of morphological parameters were measured again, including TPA, LL, and TK. CT and MRI were performed again, reflecting significant bone-to-bone fusion and successful recovery. The patient relieved the symptoms and regained his daily activities.

CONCLUSIONS

We deepen the understanding of the diagnosis and treatment of AS with rare complications of AL and ISCH. Distal PSO could be an effective option for severe AS patient.

摘要

背景与重要性

强直性脊柱炎(AS)是一种全身性慢性炎症性疾病。安德森病变(AL)是晚期AS的一种晚期并发症。特发性脊髓疝(ISCH)是一种罕见的脊髓疾病。然而,根据我们的文献综述,从未有过AS患者同时发生AL和ISCH的报道。

临床表现

一名49岁男性有30年胸腰段疼痛及活动受限病史,被诊断为AS并伴有AL和ICSH双重并发症。在矫正手术前,进行了体格检查、X线、CT、MRI及血液HLA - B27检查,并测量了一系列放射学参数,包括后凸畸形程度和T1 - 骨盆角(TPA)。手术后几天(采用远端腰大肌松解术),我们进行检查以评估患者身体状况,结果显示患者恢复显著。进行了CT血管造影(CTA),表明患者的主动脉向前移动,截骨侧未受损。再次测量了一系列形态学参数,包括TPA、腰椎前凸(LL)和胸椎后凸(TK)。再次进行CT和MRI检查,显示有明显的骨对骨融合且恢复成功。患者症状缓解,恢复了日常活动。

结论

我们加深了对伴有罕见并发症AL和ISCH的AS诊断和治疗的理解。远端腰大肌松解术可能是重度AS患者的一种有效选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/590f/11872360/4ec589c4adce/OS-17-971-g006.jpg

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