McFadden Nikia R, Brown Samantha K, Howard Shannon M, Utter Garth H
Department of Surgery, Division of Trauma and Acute Care Surgery, University of California, Davis, United States.
Department of Emergency Medicine, University of California, Davis, United States.
Surg Pract Sci. 2022 Apr 29;9:100086. doi: 10.1016/j.sipas.2022.100086. eCollection 2022 Jun.
The American Association for the Surgery of Trauma (AAST) grading system for intestinal obstruction may be a useful measure of anatomic severity, but its construct validity has not yet been evaluated in patients with either large or small bowel obstruction, using the grade applicable at initial presentation (rather than after definitive management).
We conducted a retrospective case series of adult inpatients presenting with intestinal obstruction at our center during 2008-2014. We excluded patients without confirmed intestinal obstruction, those with obstruction secondary to a hernia, those who were treated for >24 hours at another hospital, and those with a previous encounter already included in the study. We measured inter-rater reliability using a weighted kappa coefficient. We used multivariable logistic regression, accounting for sampling weights, to assess the relationship of grades with complications, 30-day mortality, and 30-day readmission.
Of 287 patients, 165 (58%) had grade I anatomic severity, 75 (26%) grade II, 23 (8%) grade III, 15 (5%) grade IV, and 9 (3%) grade V. Forty-six (16%) patients had a large bowel obstruction. There was substantial inter-rater agreement in grades [weighted kappa 0.69 (95% CI 0.47-0.91)]. Compared to grade I, grades III-V [OR 12.2 (95% CI 2.26-66.2)] but not grade II [OR 2.04 (95% CI 0.79-5.28)] were associated with increased risk of a complication. grade II [OR 7.92 (95% CI 3.27-19.2)], but not grades III-V [OR 3.56 (95% CI 0.30-42.5)] was associated with increased 30-day mortality. Grades were not associated with increased 30-day readmission.
AAST intestinal obstruction grades have predictive validity for some but not all outcomes, and may serve a useful role in the measurement of anatomic disease severity.
美国创伤外科协会(AAST)的肠梗阻分级系统可能是衡量解剖学严重程度的一项有用指标,但其结构效度尚未在小肠或大肠梗阻患者中,采用初次就诊时适用的分级(而非确定性治疗后的分级)进行评估。
我们对2008年至2014年期间在本中心就诊的成年肠梗阻住院患者进行了一项回顾性病例系列研究。我们排除了未确诊肠梗阻的患者、因疝气导致梗阻的患者、在其他医院接受治疗超过24小时的患者以及之前已纳入该研究的患者。我们使用加权kappa系数测量评分者间信度。我们采用多变量逻辑回归,并考虑抽样权重,以评估分级与并发症、30天死亡率和30天再入院率之间的关系。
287例患者中,165例(58%)解剖学严重程度为I级,75例(26%)为II级,23例(8%)为III级,15例(5%)为IV级,9例(3%)为V级。46例(16%)患者为大肠梗阻。分级之间存在较高的评分者间一致性[加权kappa 0.69(95%CI 0.47 - 0.91)]。与I级相比,III - V级[比值比(OR)12.2(95%CI 2.26 - 66.2)]而非II级[OR 2.04(95%CI 0.79 - 5.28)]与并发症风险增加相关。II级[OR 7.92(95%CI 3.27 - 19.2)]而非III - V级[OR 3.56(95%CI 0.30 - 42.5)]与30天死亡率增加相关。分级与30天再入院率增加无关。
AAST肠梗阻分级对部分而非所有结局具有预测效度,并且在衡量解剖学疾病严重程度方面可能发挥有益作用。