Belyĭ B I
Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(2):224-32.
Using clinical procedures and psychological tests, the authors examined 72 patients with tumours of the left, and 68 with those of the right frontal lobe of the brain. Tumours of the left frontal lobe were shown to be associated with such manifestations as an impoverishment of motor activity and facial mobility, speech disturbances in the form of efferent motor or dynamic aphasia, slower rate of mental processes, impaired verbal memory, diminished capacity for generalization, difficulty in switching attention to another subject, and inclination toward stereotypy. These disturbances were attended by depressive emotions at the initial, and by the apathoabulic syndrome at the later stages. Tumours located in the right frontal lobe resulted in excessive elation and euphoria, underestimation of the gravity of one's condition and anosognosia, noncritical perception of reality, lack of concentration, diminution in the volume of perception, and a tendency toward confabular additions, which was particularly manifest in the sphere of visual perceptions. The local factor appears to play the principal part in the development of psychic disorders related to the left frontal tumours, whereas in cases of the right frontal tumours, it is the size and the degree of malignancy that matter.
作者运用临床检查方法和心理测试,对72例左侧额叶肿瘤患者和68例右侧额叶肿瘤患者进行了检查。结果显示,左侧额叶肿瘤与运动活动和面部活动减少、传出性运动性失语或动态性失语形式的言语障碍、心理过程速度减慢、言语记忆受损、概括能力下降、难以将注意力转移到另一主题以及刻板行为倾向等表现相关。这些障碍在初期伴有抑郁情绪,后期则出现无欲无动综合征。位于右侧额叶的肿瘤会导致过度兴奋和欣快、对自身病情严重性估计不足和疾病感缺失、对现实缺乏批判性认知、注意力不集中、感知量减少以及虚构补充倾向,这在视觉感知领域表现得尤为明显。局部因素似乎在与左侧额叶肿瘤相关的精神障碍发展中起主要作用,而对于右侧额叶肿瘤病例,肿瘤大小和恶性程度则至关重要。