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SPING阻滞镇痛在老年体弱股骨近端骨折非手术治疗中的应用:一项回顾性队列研究

SPING Block Analgesia in Non-Operative Management of Proximal Femur Fractures in Older Adults Living with Frailty: A Retrospective Cohort Study.

作者信息

van der Velden Miriam W A, Kroes Thamar, Visschers Nick J G, de Loos Frank P J F, Janssens Pleun, Spaetgens Bart, Faes Miriam C, van den Beuken-van Everdingen Marieke H J, Suman Arnela

机构信息

Department of Pain Medicine and Palliative Care, Amphia Hospital, 4818 CK Breda, The Netherlands.

Department of Trauma Surgery, St. Antonius Hospital, 3435 CM Utrecht, The Netherlands.

出版信息

Geriatrics (Basel). 2025 Jan 10;10(1):10. doi: 10.3390/geriatrics10010010.

Abstract

: Spinal Phenol IN Glycerol (SPING) block is a novel palliative pain treatment for the non-operative management of proximal femur fractures (PFFs) in older adults living with frailty. Effective pain management that aligns with patient preferences and minimizes opioid use is critical in this setting. This study evaluated the patient, safety, and process outcomes of SPING block in this population. : A retrospective cohort study was conducted in a suburban teaching hospital from March 2021 to June 2024, which included sixty-eight older adults living with frailty that suffered from a PFF and received SPING block. Data were collected from the Electronic Patient Records. The patient living situation was visualized with a Sankey diagram. Changes in pain scores and opioid use were assessed using the Wilcoxon Signed Rank test. : The median patient age was 89 years (Interquartile range (IQR) 83-92). Most were severely or terminally ill (American Society of Anesthesiologists (ASA) ≥ 4, 72%) and had cognitive impairment or dementia (68%). SPING block was effective in 93% of patients, significantly reducing median pain scores (4 [IQR 3-5] to 0 [IQR 0-1], < 0.001) and opioid use (15 mg/day [IQR 4-30] to 0 mg/day [IQR 0-0], < 0.001). Within 24 h, 84% could sit upright and 44% could transfer between their bed and chair. The median time to discharge was one day (IQR 0-3), with a median survival of 13 days (IQR 7-44). : This study supports SPING block as a viable option for older adults living with frailty suffering from a PFF who opt for non-operative management in a palliative setting. SPING block for PFFs in a palliative setting offers effective pain relief, reduces opioid use, and enables mobility for older adults living with frailty. Follow-up is essential to monitor efficacy and safety. Prospective studies are needed to confirm these findings.

摘要

脊髓酚甘油阻滞(SPING)是一种用于体弱老年人股骨近端骨折(PFF)非手术治疗的新型姑息性疼痛治疗方法。在这种情况下,符合患者偏好并尽量减少阿片类药物使用的有效疼痛管理至关重要。本研究评估了该人群中SPING阻滞的患者、安全性和过程结果。:2021年3月至2024年6月在一家郊区教学医院进行了一项回顾性队列研究,纳入了68名患有PFF并接受SPING阻滞的体弱老年人。数据从电子病历中收集。用桑基图直观展示患者的生活状况。使用Wilcoxon符号秩检验评估疼痛评分和阿片类药物使用的变化。:患者的中位年龄为89岁(四分位间距(IQR)83 - 92岁)。大多数患者病情严重或处于终末期(美国麻醉医师协会(ASA)≥4级,72%),并有认知障碍或痴呆(68%)。SPING阻滞在93%的患者中有效,显著降低了中位疼痛评分(从4[IQR 3 - 5]降至0[IQR 0 - 1],<0.001)和阿片类药物使用量(从15毫克/天[IQR 4 - 30]降至0毫克/天[IQR 0 - 0],<0.001)。在24小时内,84%的患者能够坐直,44%的患者能够在床和椅子之间转移。中位出院时间为1天(IQR 0 - 3),中位生存期为13天(IQR 7 - 44)。:本研究支持SPING阻滞作为体弱的PFF老年人在姑息治疗中选择非手术治疗的一种可行选择。在姑息治疗中,SPING阻滞用于PFF可有效缓解疼痛,减少阿片类药物使用,并使体弱老年人能够活动。随访对于监测疗效和安全性至关重要。需要前瞻性研究来证实这些发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ff/11755650/4593c0e2f2e7/geriatrics-10-00010-g001.jpg

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