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Elevated Bone Hardness Under Denosumab Treatment, With Persisting Lower Osteocyte Viability During Discontinuation.
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Temporal patterns of osteoclast formation and activity following withdrawal of RANKL inhibition.
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Osteoclast Recycling and the Rebound Phenomenon Following Denosumab Discontinuation.
Curr Osteoporos Rep. 2022 Dec;20(6):505-515. doi: 10.1007/s11914-022-00756-5. Epub 2022 Oct 6.
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Discontinuation of Denosumab therapy for osteoporosis: A systematic review and position statement by ECTS.
Bone. 2017 Dec;105:11-17. doi: 10.1016/j.bone.2017.08.003. Epub 2017 Aug 5.
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Rebound-associated vertebral fractures after discontinuation of denosumab-from clinic and biomechanics.
Osteoporos Int. 2016 May;27(5):1917-21. doi: 10.1007/s00198-015-3458-6. Epub 2015 Dec 22.
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The comparison of alendronate and raloxifene after denosumab (CARD) study: A comparative efficacy trial.
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本文引用的文献

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Cellular signatures in human blood track bone mineral density in postmenopausal women.
JCI Insight. 2024 Nov 22;9(22):e178977. doi: 10.1172/jci.insight.178977.
3
Temporal patterns of osteoclast formation and activity following withdrawal of RANKL inhibition.
J Bone Miner Res. 2024 May 2;39(4):484-497. doi: 10.1093/jbmr/zjae023.
5
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption.
Cell. 2021 Apr 1;184(7):1940. doi: 10.1016/j.cell.2021.03.010.
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Increased osteoclastogenesis in patients with vertebral fractures following discontinuation of denosumab treatment.
Eur J Endocrinol. 2017 Jun;176(6):677-683. doi: 10.1530/EJE-16-1027. Epub 2017 Mar 10.
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Denosumab for prevention of fractures in postmenopausal women with osteoporosis.
N Engl J Med. 2009 Aug 20;361(8):756-65. doi: 10.1056/NEJMoa0809493. Epub 2009 Aug 11.

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