Hertz J B, Heisterberg L
Acta Obstet Gynecol Scand. 1985;64(2):151-6. doi: 10.3109/00016348509154709.
A prospectively collected group of 93 pregnancies complicated by threatened abortion was carefully monitored throughout pregnancy, during birth and in the perinatal period, and any deviation from a completely uneventful course was registered. Comparison was made with a selected group of 282 non-risk pregnant women. A significant association was found between threatened abortion and the overall number of complications in the second half of pregnancy requiring medical intervention and/or admission to hospital, impending pre-term birth requiring betamimetics, pre-term birth, retention of the placenta, birth weight below 2000 g, light-for-dates infants in case of pre-term birth or birth weight below 2000 g, and hyperbilirubinemia in infants with birth weight below 2000 g. The incidences of perinatal mortality and congenital malformations did not differ significantly from those of the control group. Pregnancies complicated by threatened abortion constitute a risk group requiring careful obstetric and perinatal supervision and follow-up.
前瞻性收集了93例并发先兆流产的妊娠病例,在整个孕期、分娩期间及围产期进行了仔细监测,并记录了任何偏离完全正常过程的情况。与一组选定的282例无风险孕妇进行了比较。发现先兆流产与妊娠后半期需要医疗干预和/或住院治疗的并发症总数、需要使用β-拟交感神经药的先兆早产、早产、胎盘滞留、出生体重低于2000g、早产或出生体重低于2000g时的小于胎龄儿以及出生体重低于2000g的婴儿的高胆红素血症之间存在显著关联。围产期死亡率和先天性畸形的发生率与对照组无显著差异。并发先兆流产的妊娠构成一个风险组,需要仔细的产科和围产期监护及随访。