Mitchell-Miland Chantele E, Miller Rachel G, Kriska Andrea M, Youk Ada O, Gary-Webb Tiffany L, Devaraj Susan M, Songer Thomas J, Arena Vincent C, King Wendy C, Rockette-Wagner Bonny
Department of Medicine, Division of General Internal Medicine, Institute for Clinical Research Education, University of Pittsburgh, Pittsburgh, PA, USA.
VA Pittsburgh Healthcare System University Drive Division, Center for Health Equity Research and Promotion (CHERP), Pittsburgh, PA, USA.
Transl Behav Med. 2025 Jan 16;15(1). doi: 10.1093/tbm/ibae076.
In previous efforts, health-related quality of life (HRQoL) improved for individuals at high risk of type 2 diabetes and cardiovascular disease after participation in community-based lifestyle interventions (LI) with a moderate-to-vigorous physical activity (MVPA) movement goal.
It is unknown whether HRQoL improves with LI when the primary movement goal is to reduce sedentary behavior. HRQoL changes were examined among adults with overweight and prediabetes and/or metabolic syndrome randomized to a 12-month Diabetes Prevention Program-based Group Lifestyle Balance (DPP-GLB) community LI work with goals of weight-loss and either increasing MVPA (DPP-GLB) or reducing sedentary time (GLB-SED).
Study participants (N = 269) completed the Euroqol 5 dimension 3 long (EQ5D-3L index and EuroQol Visual Analog Scale (EQVAS)-visual analog scale) at baseline, and 6 and 12 months. Paired t-tests were used to evaluate pre-to-post-intervention changes by arm.
Mean EQVAS improvements for the GLB-SED arm at 6 and 12 months were +5.6 (SE = 1.3; P < .0001) and +4.6 (SE = 1.4; P = .0006), respectively. Similar mean EQVAS improvements were reported for the DPP-GLB arm; +5.9 (SE = 1.2; P < .0001) and +4.9 (SE = 1.2; P = .0001) at 6 and 12 months, respectively. Mean EQ5D index improvements were significant in the GLB-SED arm [6 months: +0.03 (SE = 0.01; P = .004); and 12 months: +0.04 (SE = 0.01; P = .006)], but not in the DPP-GLB arm.
Participation in community LI with a primary movement goal to reduce sedentary behavior improved HRQoL at least as well as traditional LI focused more on MVPA improvement, supporting an alternate intervention strategy for those who can't or won't engage in MVPA as the primary movement goal.
在之前的研究中,2型糖尿病和心血管疾病高危个体在参与以中等至剧烈身体活动(MVPA)为运动目标的社区生活方式干预(LI)后,健康相关生活质量(HRQoL)得到改善。
当主要运动目标是减少久坐行为时,LI是否能改善HRQoL尚不清楚。在超重且患有糖尿病前期和/或代谢综合征的成年人中,研究了随机分配到基于糖尿病预防计划的为期12个月的团体生活方式平衡(DPP - GLB)社区LI的HRQoL变化,该计划的目标是减肥以及增加MVPA(DPP - GLB)或减少久坐时间(GLB - SED)。
研究参与者(N = 269)在基线、6个月和12个月时完成了欧洲五维健康量表3长版(EQ5D - 3L指数和欧洲五维视觉模拟量表(EQVAS) - 视觉模拟量表)。采用配对t检验评估各干预组干预前后的变化。
GLB - SED组在6个月和12个月时EQVAS的平均改善分别为 +5.6(标准误 = 1.3;P <.0001)和 +4.6(标准误 = 1.4;P =.0006)。DPP - GLB组也有类似的EQVAS平均改善;在6个月和12个月时分别为 +5.9(标准误 = 1.2;P <.0001)和 +4.9(标准误 = 1.2;P =.0001)。GLB - SED组EQ5D指数的平均改善显著[6个月:+0.03(标准误 = 0.01;P =.004);12个月:+0.04(标准误 = 0.01;P =.006)],但DPP - GLB组不显著。
参与以减少久坐行为为主要运动目标的社区LI至少与更侧重于改善MVPA的传统LI一样能改善HRQoL,这为那些不能或不愿将MVPA作为主要运动目标的人提供了一种替代干预策略。