Kitadai M, Itoshima T, Hattori S, Ukida M, Ito T, Ogawa H, Mizutani S, Tanaka R, Kita K, Nagashima H
Acta Med Okayama. 1985 Feb;39(1):11-8. doi: 10.18926/AMO/31539.
Sixty-seven cases of alcoholic liver disease were histologically classified into 4 groups: alcoholic liver cirrhosis (ALC), alcoholic hepatitis (AH), alcoholic liver fibrosis (ALF) and alcoholic fatty liver (AFL). They were statistically reclassified by the likelihood method using age, total alcohol intake, hepatomegaly and 12 liver function tests. A score table for likely diagnosis was constructed from the incidences of each range. The cases were re-evaluated using the score table, with an overall correct diagnosis rate of 73%. The best combination of 5 parameters included the indocyanine green plasma disappearance rate, total alcohol intake, cholesterol, choline esterase and glutamic oxaloacetic transaminase/glutamic pyruvic transaminase ratio. A correct diagnosis rate of 75% was attained using these 5 parameters, and 94% of patients were correctly diagnosed by the first or the second likelihood diagnosis. Differential diagnosis of alcoholic liver diseases was easily and confidently obtained with the likelihood score table.
67例酒精性肝病患者经组织学分类为4组：酒精性肝硬化（ALC）、酒精性肝炎（AH）、酒精性肝纤维化（ALF）和酒精性脂肪肝（AFL）。采用似然法，根据年龄、总酒精摄入量、肝肿大和12项肝功能检查对其进行统计学重新分类。根据每个范围的发生率构建了一个可能诊断的评分表。使用该评分表对病例进行重新评估，总体正确诊断率为73%。5个参数的最佳组合包括吲哚菁绿血浆消失率、总酒精摄入量、胆固醇、胆碱酯酶和谷草转氨酶/谷丙转氨酶比值。使用这5个参数的正确诊断率达到75%，94%的患者通过首次或第二次似然诊断得到正确诊断。利用似然评分表可以轻松且可靠地进行酒精性肝病的鉴别诊断。
