Van Hecke Ruth, Deconinck Frederik J A, Van Acker Emmely, Danneels Maya, Dhooge Ingeborg, Van Waelvelde Hilde, Wiersema Jan R, Maes Leen
Ghent University, Department of Rehabilitation Sciences, Corneel Heymanslaan 10 9000 Ghent, Belgium.
Ghent University, Department of Movement and Sports Sciences, Watersportlaan 2 9000 Ghent, Belgium.
Clin Neurophysiol. 2025 Mar;171:1-10. doi: 10.1016/j.clinph.2024.12.026. Epub 2025 Jan 20.
The study aimed to explore the vestibular function in children with neurodevelopmental disorders (NDDs).
Twenty-eight participants with a NDD (6 girls, 22 boys; 6-13 years; 9;3 ± 2;4 years) were enrolled in this pilot study. Sixteen participants had a single NDD (Autism Spectrum Disorder: n = 7, Developmental Coordination Disorder: n = 3; Attention Deficit/Hyperactivity Disorder: n = 6), the remaining 12 had comorbid NDDs. The integrity of the peripheral vestibular system was evaluated using ocular and cervical Vestibular Evoked Myogenic Potentials (o/cVEMP), and a video Head Impulse Test (vHIT); motor competence was assessed with the Movement Assessment Battery for Children, and the KörperkoordinationsTest für Kinder. Results were compared to an age and sex-matched control group (n = 28; 9;7 ± 1;9 years).
The NDD group exhibited significantly higher interpeak amplitudes on both VEMP tests compared to the control group (p < 0.001). No significant differences were found between the groups on vHIT measurements (p > 0.05). Among the children with NDDs, 11 (39 %) showed atypical vestibular responses, including one child with vHIT correction saccades and three children with reduced or absent otolith responses (n = 3). Additionally, eight children showed abnormally elevated otolith amplitudes (cVEMP > 4.00 µV; oVEMP > 55.00 µV).
Clinicians are encouraged to recognize the overlap and consider the possibility of vestibular alterations in individuals with NDD.
Incorporating vestibular assessments into routine clinical evaluations, particularly in children with NDD who exhibit delayed motor development, balance issues, hearing loss, or vestibular-related symptoms, is strongly recommended.
