Kallok M J, Wibel F H, Bourland J D, Tacker W A, Schollmeyer M P, Van Vleet J F
Am Heart J. 1985 Apr;109(4):821-6. doi: 10.1016/0002-8703(85)90645-3.
A catheter-mounted electrode system designed for intracavitary ventricular defibrillation was implanted in the right ventricular apex of 12 dogs. Defibrillation thresholds were obtained in all dogs at the time of implant using an external defibrillator. Roentgenograms obtained 3 weeks after catheter implantation revealed that six dogs had catheters intact at the site of implant (group A) and six dogs had catheters that had dislodged from the original implant site (group B). There were no statistically significant differences (p less than 0.05) in mean body weight or mean defibrillation threshold between group A and group B dogs, respectively, at implant. Defibrillation thresholds were obtained for both groups of animals at 5, 12, and 26 weeks after catheter implantation. At all post implant monitors mean threshold for group B was significantly higher (p less than 0.05) than mean threshold for group A. Moreover, mean defibrillation threshold for both groups had increased by week 5 and remained stable through week 26. Catheter dislodgement increases defibrillation threshold, but does not prevent successful defibrillation. Also, defibrillation threshold increases to a stable value by 5 weeks post implant.
一种专为心腔内心室除颤设计的导管安装式电极系统被植入12只犬的右心室心尖。在植入时使用体外除颤器获得了所有犬的除颤阈值。导管植入3周后获得的X线片显示，6只犬的导管在植入部位保持完整（A组），6只犬的导管已从原植入部位移位（B组）。A组和B组犬在植入时的平均体重或平均除颤阈值分别无统计学显著差异（p<0.05）。在导管植入后5周、12周和26周分别获得两组动物的除颤阈值。在所有植入后的监测中，B组的平均阈值显著高于A组（p<0.05）。此外，两组的平均除颤阈值在第5周时均升高，并在第26周时保持稳定。导管移位会增加除颤阈值，但并不妨碍成功除颤。而且，除颤阈值在植入后5周时增加到一个稳定值。
