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The first case of paraneoplastic pemphigus positive for IgG autoantibodies against integrin α6.

作者信息

Li Ying, Dong Yunmei, Zeng Xin, Li Wei, Zhou Yu, Li Xiaoguang

机构信息

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

Department of Dermatovenereology, Rare Disease Center, West China Hospital, Sichuan University, Chengdu, China.

出版信息

An Bras Dermatol. 2025 Mar-Apr;100(2):380-383. doi: 10.1016/j.abd.2024.04.016. Epub 2025 Jan 22.

DOI:10.1016/j.abd.2024.04.016
PMID:39848833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11963105/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2afe/11963105/de8eb6904ff9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2afe/11963105/0bd7924b6a5e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2afe/11963105/78933e746eca/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2afe/11963105/1a17b1db81a3/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2afe/11963105/de8eb6904ff9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2afe/11963105/0bd7924b6a5e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2afe/11963105/78933e746eca/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2afe/11963105/1a17b1db81a3/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2afe/11963105/de8eb6904ff9/gr4.jpg

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本文引用的文献

1
A Chinese case of concurrent anti-laminin γ1 pemphigoid and anti-laminin 332-type mucous membrane pemphigoid.一例中国并发抗层粘连蛋白γ1类天疱疮和抗层粘连蛋白332型黏膜类天疱疮的病例。
J Dermatol. 2023 Feb;50(2):e69-e71. doi: 10.1111/1346-8138.16513. Epub 2022 Jul 11.
2
Case Report: Mucous Membrane Pemphigoid With IgG and IgA Anti-Laminin γ1 Antibodies and IgA Anti-Laminin α5 Antibodies.病例报告：伴 IgG 和 IgA 抗层粘连蛋白 γ1 抗体及 IgA 抗层粘连蛋白 α5 抗体的黏膜性大疱性皮病。
Front Immunol. 2022 Jun 1;13:903174. doi: 10.3389/fimmu.2022.903174. eCollection 2022.
3
Paraneoplastic Pemphigus: Paraneoplastic Autoimmune Disease of the Skin and Mucosa.
副肿瘤天疱疮：皮肤和黏膜的副肿瘤自身免疫性疾病。
Front Immunol. 2019 Jun 4;10:1259. doi: 10.3389/fimmu.2019.01259. eCollection 2019.
4
Integrin β4 is a major target antigen in pure ocular mucous membrane pemphigoid.整合素β4是单纯眼黏膜类天疱疮中的主要靶抗原。
Eur J Dermatol. 2016 Jun 1;26(3):247-53. doi: 10.1684/ejd.2016.2772.
5
Clinical and immunological findings in 104 cases of paraneoplastic pemphigus.104 例副肿瘤性天疱疮的临床和免疫学研究。
Br J Dermatol. 2015 Dec;173(6):1447-52. doi: 10.1111/bjd.14162. Epub 2015 Nov 14.
6
Antigen specificity in subsets of mucous membrane pemphigoid.黏膜类天疱疮各亚组中的抗原特异性。
J Invest Dermatol. 2006 Dec;126(12):2631-6. doi: 10.1038/sj.jid.5700465. Epub 2006 Jun 29.
7
Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia.副肿瘤性天疱疮。一种与肿瘤形成相关的自身免疫性黏膜皮肤疾病。
N Engl J Med. 1990 Dec 20;323(25):1729-35. doi: 10.1056/NEJM199012203232503.