Badon S J, Ansell J, Smith T W, Coslovsky R, Gill L, Woda B A
Am J Clin Pathol. 1985 Apr;83(4):509-12. doi: 10.1093/ajcp/83.4.509.
Myeloid metaplasia involving the central nervous system is a rare occurrence most frequently found as an incidental finding at autopsy. A case is presented of a 56-year-old man with myeloid metaplasia and myelofibrosis, who developed diabetes insipidus. Postmortem examination revealed posterior pituitary involvement by extramedullary hematopoiesis with fibrosis and gliosis. Diabetes insipidus caused by extramedullary hematopoiesis is a rare event and is thus noteworthy.
累及中枢神经系统的髓样化生较为罕见,多在尸检时偶然发现。本文报告一例56岁男性患者,患有髓样化生和骨髓纤维化,并出现尿崩症。尸检显示垂体后叶受髓外造血累及,伴有纤维化和胶质增生。髓外造血引起的尿崩症是罕见事件,因此值得关注。