Nolph K D
Proc Eur Dial Transplant Assoc. 1979;16:277-85.
The peritoneal dialysis system is a sophisticated dialyser. It probably represents a capillary kidney regulating the number of capillaries perfused, the nature of capillaries perfused, and the overall permeability of its membranes. Its sophistication far exceeds that available with extracorporeal man-made haemodialysis systems. However, because of limited pore area and inaccessible fluid film resistances, it will never be an efficient dialyser for small solute removal. One way to overcome this intrinsic inefficiency is to utilise CAPD which trades efficiency for time. Our first two years of experience with CAPD have answered many initial questions, at least in a preliminary fashion. The future of CAPD has exciting potential, but many questions remain.
腹膜透析系统是一种复杂的透析器。它可能代表了一个毛细血管肾脏，调节着灌注的毛细血管数量、灌注的毛细血管性质以及其膜的整体通透性。其复杂性远远超过体外人造血液透析系统。然而，由于孔隙面积有限和存在难以测量的液膜阻力，它永远不会成为一种高效的小分子溶质清除透析器。克服这种内在低效性的一种方法是采用持续性非卧床腹膜透析（CAPD），它以时间换取效率。我们开展CAPD的头两年经验至少初步回答了许多最初的问题。CAPD的未来有着令人兴奋的潜力，但仍存在许多问题。
