Klein H Z, Shields M B, Ernest J T
Am J Ophthalmol. 1985 Apr 15;99(4):392-5. doi: 10.1016/0002-9394(85)90003-0.
Forty-five adults with primary open-angle glaucoma received argon laser trabeculoplasty in two stages (180 degrees in each session) separated by one month. The indication for argon laser trabeculoplasty in each case was uncontrolled glaucoma consisting of progressive optic disk cupping and visual field loss despite maximally tolerable medication. A P value of .01 by Student's two-tailed paired t-test was used for statistical significance in the analysis of the intraocular pressure data. In most cases, the greatest reduction in intraocular pressure followed stage 1. Some patients received no additional benefit from stage 2; in other cases, the second stage was not only beneficial but provided most of the reduction in pressure. The pretreatment intraocular pressure level influenced the response to laser therapy. Patients with the highest pretreatment intraocular pressures received the most benefit. Both stages were complicated by a transient postoperative increase of 5 mm Hg or more in 12 patients (approximately 19%).
45例原发性开角型青光眼成人患者接受了氩激光小梁成形术，分两个阶段进行（每次180度），间隔1个月。每个病例进行氩激光小梁成形术的指征是尽管使用了最大耐受剂量的药物，但青光眼仍未得到控制，表现为进行性视盘凹陷和视野缺损。在分析眼压数据时，采用学生双尾配对t检验，P值为0.01作为统计学显著性标准。在大多数情况下，眼压最大降幅出现在第1阶段后。一些患者在第2阶段未获得额外益处；在其他情况下，第2阶段不仅有益，而且提供了大部分的眼压降低。治疗前眼压水平影响对激光治疗的反应。治疗前眼压最高的患者受益最大。两个阶段均有12例患者（约19%）术后眼压短暂升高5 mmHg或更多，出现了并发症。
