Okoli George N, Soos Alexandra E, Etsell Katharine, Grossman Moon Alexandra, Kimmel Supron Hannah, Grewal Avneet, Neilson Christine J, Richardson Caroline, Harper Diane M
Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
University of Michigan Medical School, University of Michigan.
Behav Med. 2025 Jul-Sep;51(3):185-206. doi: 10.1080/08964289.2024.2447358. Epub 2025 Jan 24.
Human papillomavirus (HPV) vaccination among males is poorly understood. We systematically reviewed individual socioeconomic/health-related characteristics associated with HPV vaccine initiation and vaccination series completion among males in the United States. We searched for literature up to August 1, 2023, and pooled appropriate multivariable-adjusted results using an inverse variance random effects model, with results expressed as odds ratios. Among pediatric males (<18 years old), we observed moderately increased odds of vaccine initiation in urban residence, with being a Black/Hispanic male versus White male, public versus private health insurance, and visiting a health care provider in the past year. Influenza vaccination in the past year strongly increased the odds. Further, urban residence and having a parent with lower/no education moderately increased the odds of vaccination series completion, whereas influenza vaccination strongly increased the odds. Among adult males (≥18 years old), we observed moderately increased odds of vaccine initiation in the US-born, unemployed, unmarried/separated/divorced/widowed; among the states in the Northern versus Western region; having had a sexually transmitted infection; and being gay/bisexual. Younger age, living in the states in the Northern versus Southern region, having health insurance, and having visited a health care provider in the past year strongly increased the odds. Further, higher education, unmarried/separated/divorced/widowed, being a White male versus Black male, living in the states in the Northern versus Western region, and having a primary care physician moderately increased the odds of vaccination series completion, whereas having health insurance and being gay/bisexual strongly increased the odds. These findings may inform age-targeted future vaccination program planning.
男性人乳头瘤病毒（HPV）疫苗接种情况鲜为人知。我们系统回顾了与美国男性HPV疫苗接种起始及完成接种系列相关的个体社会经济/健康相关特征。我们检索了截至2023年8月1日的文献，并使用逆方差随机效应模型汇总了适当的多变量调整结果，结果以比值比表示。在儿科男性（<18岁）中，我们观察到城市居住、黑人/西班牙裔男性与白人男性相比、公立与私立医疗保险、以及过去一年就诊于医疗服务提供者的情况下，疫苗接种起始的几率适度增加。过去一年接种流感疫苗会大幅增加接种几率。此外，城市居住以及父母教育程度较低/无教育会适度增加完成接种系列的几率，而接种流感疫苗会大幅增加几率。在成年男性（≥18岁）中，我们观察到在美国出生、失业、未婚/分居/离婚/丧偶的情况下，疫苗接种起始的几率适度增加；在北部与西部地区的各州中；有性传播感染；以及为男同性恋者/双性恋者。年龄较小、居住在北部与南部地区的各州、有医疗保险、以及过去一年就诊于医疗服务提供者会大幅增加接种几率。此外，高等教育、未婚/分居/离婚/丧偶、白人男性与黑人男性相比、居住在北部与西部地区的各州、以及有初级保健医生会适度增加完成接种系列的几率，而有医疗保险以及为男同性恋者/双性恋者会大幅增加几率。这些发现可能为未来有针对性的年龄接种计划规划提供参考。
