King R B, Bechtold D L
Ann Emerg Med. 1985 Apr;14(4):362-4. doi: 10.1016/s0196-0644(85)80106-2.
We present the case of a 28-year-old man on chronic warfarin therapy who sustained a minor muscle tear and developed increasing pain and a flexure contracture of the right hip. Surgical exploration revealed an iliopsoas hematoma and femoral nerve entrapment, resulting in a femoral nerve palsy and partial loss of quadriceps functions. Anticoagulant-induced femoral nerve palsy represents the most common form of warfarin-induced peripheral neuropathy; it is characterized by severe pain in the inguinal region, varying degrees of motor and sensory impairment, and flexure contracture of the involved extremity.
我们报告一例28岁接受慢性华法林治疗的男性病例,该患者发生轻微肌肉撕裂,随后右髋部疼痛加剧并出现屈曲挛缩。手术探查发现髂腰肌血肿和股神经受压,导致股神经麻痹和股四头肌功能部分丧失。抗凝剂诱发的股神经麻痹是华法林诱发的周围神经病变最常见的形式;其特征为腹股沟区剧痛、不同程度的运动和感觉障碍以及受累肢体的屈曲挛缩。