Chapelon J, Sourdet S, Angioni D, Steinmeyer Z, Briand M, Rolland Y, Abellan van Kan G
IHU HealthAge, Frailty Clinic, Toulouse University Hospital, Gérontopôle, La Cité de la Santé, Hôpital La Grave, Place Lange, Toulouse 31059, France.
IHU HealthAge, Frailty Clinic, Toulouse University Hospital, Gérontopôle, La Cité de la Santé, Hôpital La Grave, Place Lange, Toulouse 31059, France.
J Frailty Aging. 2025 Feb;14(1):100003. doi: 10.1016/j.tjfa.2024.100003. Epub 2025 Jan 1.
Body mass index (BMI) determines general corpulence and health, whatever age, sex or clinical background. Normal BMI (18.5-24.9 kgm) is defined as healthy, normal, weight leading to a false impression that no intervention is needed.
Assess the prevalence of body impairments in the presence of normal BMI.
Cross-sectional design. Bivariate and a multivariate regression analysis assessed the association of body composition with clinical parameters in the presence of normal BMI.
Community dwelling older adults attending the Toulouse Frailty Clinic at the University Hospital, Toulouse.
876 community dwelling, autonomous older adults, 70 years and over.
Dual X-ray Absorptiometry (DXA) assessment, and cognitive, physical, nutritional, and demographic evaluations were included in the present analysis.
Of the initial sample, 347 (39.61 %) patients had normal BMI, and among them, 152 (43.80 %) had low lean mass, 144 (41.49 %) were osteoporotic and 2 (0.58 %) increased fat mass. A poor nutritional status (Mini-Nutritional Assessment score, MNA-score, <24) was the only independent variable associated with body impairments in the presence of normal BMI (Odd Ratio 2.83; 95 % Confidence Interval 1.64-4.89).
Nearly 70 % of the adults with normal BMI had at least one impairment in body composition (low lean mass, osteoporosis, or obesity). In the light of the present study, older adults with normal BMI and an MNA-score under 24 should be assessed with DXA to identify the age-associated impairments in body composition in order to lead to specific interventions.
无论年龄、性别或临床背景如何，体重指数（BMI）都能反映总体肥胖程度和健康状况。正常BMI（18.5 - 24.9千克/平方米）被定义为健康、正常体重，这可能会让人产生不需要干预的错觉。
评估BMI正常情况下身体损伤的患病率。
横断面设计。双变量和多变量回归分析评估了BMI正常时身体成分与临床参数之间的关联。
图卢兹大学医院图卢兹衰弱诊所的社区居住老年人。
876名70岁及以上的社区居住、生活自理的老年人。
本分析包括双能X线吸收法（DXA）评估以及认知、身体、营养和人口统计学评估。
在初始样本中，347名（39.61%）患者BMI正常，其中152名（43.80%）瘦体重低，144名（41.49%）患有骨质疏松症，2名（0.58%）脂肪量增加。营养状况不佳（微型营养评定量表评分，MNA评分，<24）是BMI正常情况下与身体损伤相关的唯一独立变量（比值比2.83；95%置信区间1.64 - 4.89）。
BMI正常的成年人中近70%至少有一种身体成分损伤（瘦体重低、骨质疏松或肥胖）。根据本研究，BMI正常且MNA评分低于24的老年人应进行DXA评估，以识别与年龄相关的身体成分损伤，从而采取特定干预措施。
