Lombardo Riccardo, Romagnoli Matteo, Splendore Chiara, Sarcinelli Luca, Turchi Beatrice, Gallo Giacomo, Tema Giorgia, Franco Antonio, Nacchia Antonio, Fusco Ferdinando, Al Salhi Yazan, Fuschi Andrea, Pastore Antonio, Cicione Antonio, Tubaro Andrea, De Nunzio Cosimo
Department of Urology, Sapienza University of Rome, 00185 Rome, Italy.
Healthcare (Basel). 2025 Jan 18;13(2):185. doi: 10.3390/healthcare13020185.
: The impact of lifestyle on lower urinary tract symptoms has been deeply evaluated in recent years; however, studies in the young population are missing. The aim of this study is to evaluate the impact of alcohol intake, tobacco and cannabinoid smoking, physical activity, and dietary regime on urinary symptoms and sexual function in young adults under 30 years of age. : A prospectively enrolled population of healthy young adults of both sexes under 30 years of age was selected. Young people with comorbidities were excluded. All participants were assessed by completing an anonymous questionnaire which included questions on medical history, lifestyle, smoking and alcohol intake, urinary symptoms, and sexual function only in male subjects. The questionnaire was postponed in case there was an acute pathology. : Overall, 802 young adults were prospectively enrolled, of whom 44% were male and 56% female, with a median age of 26 (23/28) years. In our population, 580/818 (70.9%) subjects presented an IPSS ≥ 3. In the analysis of the association between urinary symptoms and smoking, smokers presented urinary symptoms more frequently than nonsmokers (76% vs. 61%; < 0.05). No association between urinary symptoms and alcohol intake, cannabinoid smoking, physical activity, and dietary regimen was recorded. On multivariable analysis, smokers had an almost doubled risk of urinary symptoms compared to nonsmokers (OR: 1.78; = 0.001). : In conclusion, we demonstrated how even in the young population there can be a correlation between LUTSs and different lifestyles.
近年来，生活方式对下尿路症状的影响已得到深入评估；然而，针对年轻人群的研究尚缺。本研究旨在评估饮酒、吸烟、吸食大麻、体育活动及饮食方式对30岁以下年轻成年人泌尿症状及性功能的影响。
选取了前瞻性纳入的30岁以下健康年轻成年人队列，排除了患有合并症的年轻人。所有参与者均通过填写一份匿名问卷进行评估，问卷内容包括病史、生活方式、吸烟与饮酒情况、泌尿症状，仅男性参与者还包括性功能相关问题。若存在急性病变，则推迟填写问卷。
总体而言，前瞻性纳入了802名年轻成年人，其中44%为男性，56%为女性，中位年龄为26（23/28）岁。在我们的研究人群中，580/818（70.9%）名受试者国际前列腺症状评分（IPSS）≥3。在泌尿症状与吸烟的相关性分析中，吸烟者出现泌尿症状的频率高于不吸烟者（76%对61%；P<0.05）。未记录到泌尿症状与饮酒、吸食大麻、体育活动及饮食方式之间的相关性。多变量分析显示，与不吸烟者相比，吸烟者出现泌尿症状的风险几乎翻倍（比值比：1.78；P = 0.001）。
总之，我们证明了即使在年轻人群中，下尿路症状与不同生活方式之间也可能存在关联。
