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多学科外阴癌管理:皮肤科医生的观点

Multidisciplinary Vulvar Cancer Management: The Dermatologist's Perspective.

作者信息

Cebolla-Verdugo Marta, Cassini-Gómez de Cádiz Victor Alfredo, Velasco-Amador Juan Pablo, Zulaika-Lloret María, Almazán-Fernández Francisco Manuel, Ruiz-Villaverde Ricardo

机构信息

Department of Dermatology, Hospital Universitario San Cecilio, Avenida del Conocimiento s/n, 18016 Granada, Spain.

Instituto Biosanitario de Granada, Ibs, 18012 Granada, Spain.

出版信息

Life (Basel). 2024 Dec 27;15(1):19. doi: 10.3390/life15010019.

Abstract

Vulvar cancer, particularly squamous cell carcinoma (SCC) and melanoma, poses significant diagnostic and therapeutic challenges due to its complex presentation and high rates of postoperative complications. Effective management requires a multidisciplinary approach, integrating the expertise of gynecologic oncologists, dermatologists, plastic surgeons, and other specialists. This review highlights the dermatologist's role in supporting early diagnosis, addressing predisposing conditions such as lichen sclerosus, and managing postoperative wound complications, including surgical site infections and dehiscence. Through two clinical cases, we illustrate how dermatological expertise complements surgical efforts by employing advanced wound care techniques such as negative pressure wound therapy and tailored dressing protocols. By collaborating closely with gynecologists and other team members, dermatologists enhance patient outcomes, ensuring timely recovery and the prevention of long-term sequelae. The article also discusses recent advances in treatment guidelines and targeted therapies, underscoring the importance of integrated care for optimizing patient outcomes in vulvar cancer.

摘要

外阴癌,尤其是鳞状细胞癌(SCC)和黑色素瘤,因其临床表现复杂且术后并发症发生率高,给诊断和治疗带来了重大挑战。有效的管理需要多学科方法,整合妇科肿瘤学家、皮肤科医生、整形外科医生和其他专家的专业知识。本综述强调了皮肤科医生在支持早期诊断、处理诸如硬化性苔藓等易感疾病以及管理术后伤口并发症(包括手术部位感染和裂开)方面的作用。通过两个临床病例,我们展示了皮肤科专业知识如何通过采用负压伤口治疗和定制敷料方案等先进伤口护理技术来补充手术努力。通过与妇科医生和其他团队成员密切合作,皮肤科医生改善了患者的治疗效果,确保了及时康复并预防了长期后遗症。本文还讨论了治疗指南和靶向治疗的最新进展,强调了综合护理对于优化外阴癌患者治疗效果的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8028/11767040/62bfce11471c/life-15-00019-g001.jpg

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