Saxena Siddanth, Lis Manuel J
INTEXTER-UPC, Surface Science Laboratory, Colon 15, 08222 Terrassa, Spain.
Molecules. 2025 Jan 13;30(2):293. doi: 10.3390/molecules30020293.
Metal-organic frameworks (MOFs) have become a highly usable system in various sectors because of their highly ordered structure and high porosity providing them with high storage capacity. However, their use is sometimes forbidden in the food industry due to the presence of some organic compounds which have undesirable effects. Cyclodextrins, which are considered GRAS (Generally Recognized as Safe) by the FDA, comes as a very good alternative to previously used compounds for the development of the MOFs to be used in the food packaging industry, especially in the packaging sector. The cyclodextrin MOF does possess edible, biocompatible, as well as biodegradable characteristics and due to these reasons, they have gained attention from researchers in the food industry. In this review, we focus on the recent advancements in the field of CD MOFs. We have emphasized the synthesis of these MOFs through different techniques, formations of their inclusion complex with bioactive compounds, and their characterization. Finally, we discussed the use of CD MOFs as carriers for various highly volatile bioactive compounds and their ability to increase the solubility and stability of these bioactive compounds.
金属有机框架材料(MOFs)因其高度有序的结构和高孔隙率赋予其高存储容量,已成为各个领域中极具实用性的体系。然而,由于存在一些具有不良影响的有机化合物,它们在食品工业中的使用有时会被禁止。环糊精被美国食品药品监督管理局(FDA)视为“一般认为安全”(GRAS)物质,是食品包装行业中用于开发MOFs的先前使用化合物的非常好的替代品,尤其是在包装领域。环糊精MOF确实具有可食用、生物相容以及可生物降解的特性,基于这些原因,它们受到了食品行业研究人员的关注。在本综述中,我们聚焦于环糊精MOFs领域的最新进展。我们强调了通过不同技术合成这些MOFs、它们与生物活性化合物形成包合物以及它们的表征。最后,我们讨论了环糊精MOFs作为各种高挥发性生物活性化合物载体的用途以及它们提高这些生物活性化合物溶解度和稳定性的能力。