Metal-organic frameworks (MOFs) have become a highly usable system in various sectors because of their highly ordered structure and high porosity providing them with high storage capacity. However, their use is sometimes forbidden in the food industry due to the presence of some organic compounds which have undesirable effects. Cyclodextrins, which are considered GRAS (Generally Recognized as Safe) by the FDA, comes as a very good alternative to previously used compounds for the development of the MOFs to be used in the food packaging industry, especially in the packaging sector. The cyclodextrin MOF does possess edible, biocompatible, as well as biodegradable characteristics and due to these reasons, they have gained attention from researchers in the food industry. In this review, we focus on the recent advancements in the field of CD MOFs. We have emphasized the synthesis of these MOFs through different techniques, formations of their inclusion complex with bioactive compounds, and their characterization. Finally, we discussed the use of CD MOFs as carriers for various highly volatile bioactive compounds and their ability to increase the solubility and stability of these bioactive compounds.