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无麸质饮食与健康相关生活质量:经过验证的希腊语版乳糜泻饮食依从性测试

Gluten-Free Diet and Health-Related Quality of Life: The Validated Hellenic Version of the Celiac Dietary Adherence Test.

作者信息

Psylinakis Emmanuel, Manidis Alexios, Makris Fotios, Thalassinos Nikolaos, Markaki Anastasia, Kounelaki Vasileia, Sfakianaki Eirini, Spyridaki Aspasia

机构信息

Department of Nutrition and Dietetics Sciences, Hellenic Mediterranean University (HMU), Trypitos Area, 72300 Sitia, Greece.

Institute of Agri-Food and Life Sciences, Hellenic Mediterranean University Research Centre, 71410 Heraklion, Greece.

出版信息

Nutrients. 2025 Jan 20;17(2):353. doi: 10.3390/nu17020353.

Abstract

BACKGROUND/OBJECTIVES: A reliable assessment of gluten-free diet (GFD) adherence is essential for managing celiac disease (CD). This study aimed to validate the Hellenic version of the Celiac Disease Adherence Test (H-CDAT) to evaluate adherence levels and explore the impact of dietary adherence on health-related quality of life (HRQoL)-both of which have never been objectively assessed in Greek CD patients.

METHODS

The study included 102 adult CD patients who completed H-CDAT, diet-related questions, and the 36-Item Short Form Health Survey (SF-36).

RESULTS

H-CDAT demonstrated good psychometric properties and showed multiple strong correlations with HRQoL dimensions. H-CDAT adherence was Good in 38.2%, Moderate in 42.2%, and Poor in 19.6% of patients, despite their perception of effective adherence, with 51% never having visited a dietitian for guidance on a GFD. Patients scored significantly lower across most HRQoL dimensions compared to the general Greek population. When stratified into the three adherence categories, striking differences emerged between Good and Moderate adherence across both physical and mental health domains, highlighting that moderate adherence is not sufficient for optimal health outcomes.

CONCLUSIONS

These findings emphasize the critical role of strict GFD adherence in improving overall health and underscore the importance of dietetic intervention for achieving optimal patient outcomes.

摘要

背景/目的:对面筋不耐受饮食(GFD)依从性进行可靠评估对于管理乳糜泻(CD)至关重要。本研究旨在验证希腊版乳糜泻依从性测试(H-CDAT),以评估依从水平,并探讨饮食依从性对健康相关生活质量(HRQoL)的影响——这两个方面在希腊乳糜泻患者中从未得到过客观评估。

方法

该研究纳入了102名成年乳糜泻患者,他们完成了H-CDAT、饮食相关问题以及36项简短健康调查(SF-36)。

结果

H-CDAT显示出良好的心理测量特性,并与HRQoL维度呈现出多重强相关性。尽管患者自认为依从性良好,但H-CDAT依从性良好的患者占38.2%,中等的占42.2%,差的占19.6%,其中51%的患者从未就GFD接受过营养师的指导。与希腊普通人群相比,患者在大多数HRQoL维度上的得分显著较低。当分为三个依从类别时,在身心健康领域,良好依从性和中等依从性之间出现了显著差异,这突出表明中等依从性不足以实现最佳健康结果。

结论

这些发现强调了严格遵循GFD在改善整体健康方面的关键作用,并强调了饮食干预对于实现最佳患者结果的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b6/11768578/ea13a0ed4983/nutrients-17-00353-g001.jpg

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