Pallin Jennifer A, Lockhart Michael, O'Loughlin Aonghus, Gallagher David, Kearns Stephen R, Dinneen Sean F, Bergin Diane
Converge: Centre for Chronic Disease and Population Health Research, School of Population Health, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
School of Public Health, University College Cork, Cork, Ireland.
Diabet Med. 2025 Jun;42(6):e15517. doi: 10.1111/dme.15517. Epub 2025 Jan 24.
To describe the sonographic features of active Charcot neuro-osteoarthropathy (CNO) and assess the potential role of ultrasound in identifying those with active CNO.
Using a prospective case-series study design we assessed the sonographic features of 14 patients with a diagnosis of diabetes presenting with clinical signs and symptoms suspicious for active CNO. Patients had standard weight-bearing plain X-Ray and, where possible, MRI to evaluate the presence of active CNO. Ultrasound was performed bilaterally to assess for subcutaneous oedema, intra-articular and peri-articular colour flow. The spectral waveform morphology, peak systolic velocity and resistive index of the dorsalis pedis arteries of both feet were also documented.
Following clinical and radiological (X-ray and MRI) assessment, 50% (n = 7) were diagnosed with active CNO. Of those with a confirmed diagnosis, ≥3 sonographic features suggestive of active CNO were observed.
Ultrasound combined with clinical presentation and medical history may support decision making around the diagnosis of CNO at the bedside.
描述活动性夏科氏神经骨关节病（CNO）的超声特征，并评估超声在识别活动性CNO患者中的潜在作用。
采用前瞻性病例系列研究设计，我们评估了14例诊断为糖尿病且出现疑似活动性CNO临床症状和体征患者的超声特征。患者进行了标准负重X线平片检查，并在可能的情况下进行了MRI检查，以评估活动性CNO的存在。双侧进行超声检查，以评估皮下水肿、关节内和关节周围血流情况。还记录了双足足背动脉的频谱波形形态、收缩期峰值流速和阻力指数。
经过临床和放射学（X线和MRI）评估，50%（n = 7）被诊断为活动性CNO。在确诊的患者中，观察到≥3个提示活动性CNO的超声特征。
超声结合临床表现和病史可能有助于床边CNO诊断的决策。
