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通过自旋标记测量流动中红细胞的取向II——红细胞取向速率的唯象模型

Measurement of erythrocyte orientation in flow by spin labeling II--phenomenological models for erythrocyte orientation rate.

作者信息

Bitbol M, Quemada D

出版信息

Biorheology. 1985;22(1):31-42. doi: 10.3233/bir-1985-22103.

DOI:10.3233/bir-1985-22103
PMID:3986317
Abstract

We present two phenomenological models describing the flowing erythrocyte orientation rate. The first concerns the onset of a stable orientation in a very dilute erythrocyte suspension. It is based on a simple formula for erythrocyte elongation as a function of shear stress, and we assume that beyond a threshold of elongation, erythrocytes take on a stable orientation, while below this threshold, they have a flipping motion. We extend this model to high hematocrit values assuming that the effect of red cell collisions imposes a random moment to each erythrocyte, shifting it from its stable orientation. We obtain an approximate expression for erythrocyte orientation rate as a function of shear rate and then we compare these results to our experimental data in part III of this series.

摘要

我们提出了两个描述流动红细胞取向速率的唯象模型。第一个模型涉及非常稀的红细胞悬浮液中稳定取向的起始。它基于一个简单的公式,该公式将红细胞伸长表示为剪切应力的函数,并且我们假设超过伸长阈值时,红细胞呈现稳定取向,而低于此阈值时,它们具有翻转运动。我们将此模型扩展到高血细胞比容值,假设红细胞碰撞的影响给每个红细胞施加一个随机力矩,使其偏离稳定取向。我们得到了红细胞取向速率作为剪切速率函数的近似表达式,然后将这些结果与本系列第三部分中的实验数据进行比较。

相似文献

1
Measurement of erythrocyte orientation in flow by spin labeling II--phenomenological models for erythrocyte orientation rate.通过自旋标记测量流动中红细胞的取向II——红细胞取向速率的唯象模型
Biorheology. 1985;22(1):31-42. doi: 10.3233/bir-1985-22103.
2
Measurement of erythrocyte orientation in flow by spin labeling III--erythrocyte orientation and rheological conditions.通过自旋标记法测量流动中红细胞的取向III——红细胞取向与流变学条件
Biorheology. 1985;22(1):43-53. doi: 10.3233/bir-1985-22104.
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Measurement of the erythrocyte orientation in a flow by spin labeling.通过自旋标记测量流动中红细胞的取向。
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Spin-label studies of erythrocyte deformability. IV. Relation of electron spin resonance spectral change with deformation and orientation of erythrocytes in shear flow.红细胞变形性的自旋标记研究。IV. 电子自旋共振光谱变化与剪切流中红细胞变形和取向的关系。
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Developing red cell flow orientation shown by changes in blood reflectivity.通过血液反射率变化显示红细胞流动方向的发展。
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Red blood cell orientation in orbit C = 0.轨道中红细胞取向C = 0。
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[Method for measuring the orientation rate of flowing erythrocytes by spin labeling].
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Binding of two spin-labelled derivatives of chlorpromazine to human erythrocytes.氯丙嗪的两种自旋标记衍生物与人红细胞的结合。
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Deformation and orientation of red blood cells in a simple shear flow. Theoretical study and approach at small angle light scattering.简单剪切流中红细胞的变形与取向。小角度光散射的理论研究与方法。
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Quantitative Measurement and Evaluation of Red Blood Cell Aggregation in Normal Blood Based on a Modified Hanai Equation.
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A flow EPR study of deformation and orientation characteristics of erythrocyte ghosts: effects of lysing and resealing conditions.红细胞血影变形和取向特性的流动电子顺磁共振研究:溶血和重新封闭条件的影响。
J Membr Biol. 1988 Sep;104(3):265-73. doi: 10.1007/BF01872328.
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A flow EPR study of deformation and orientation characteristics of erythrocyte ghosts: a possible effect of an altered state of cytoskeletal network.红细胞血影变形和取向特征的流动电子顺磁共振研究:细胞骨架网络状态改变的可能影响。
J Membr Biol. 1988;101(1):57-65. doi: 10.1007/BF01872820.
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Spin label study of erythrocyte deformability. Ca2+-induced loss of deformability and the effects of stomatocytogenic reagents on the deformability loss in human erythrocytes in shear flow.红细胞变形性的自旋标记研究。钙离子诱导的变形性丧失以及口形红细胞生成试剂对剪切流中人类红细胞变形性丧失的影响。
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