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全胃切除及大量饮酒诱发的肺放线菌病:一例报告

Pulmonary Actinomycosis Induced by Total Gastrectomy and Heavy Alcohol Drinking: A Case Report.

作者信息

Ohnuma Sana, Takizawa Keita, Ozasa Kana, Nakata Jumi, Noma Noboru

机构信息

Department of Oral Medicine, Nihon University School of Dentistry, Tokyo, JPN.

Division of Internal Medicine, Towa Hospital, Tokyo, JPN.

出版信息

Cureus. 2024 Dec 26;16(12):e76398. doi: 10.7759/cureus.76398. eCollection 2024 Dec.

Abstract

Combined risk factors such as total gastrectomy, heavy alcohol consumption, smoking, and poor oral hygiene may contribute to the development of pulmonary actinomycosis. Here, we present a rare case of pulmonary actinomycosis triggered by total gastrectomy and heavy alcohol consumption. The patient presented with hemoptysis and a suspected lung mass. With a history of total gastrectomy and heavy alcohol consumption, the patient underwent imaging studies that initially suggested lung cancer. While imaging studies initially suggested lung cancer, multiple bronchoscopic examinations ultimately led to a diagnosis of pulmonary actinomycosis, following an initial biopsy that revealed chronic bronchitis. The patient was treated with oral amoxicillin (1,500 mg/day for six months) alongside comprehensive dental care, including periodontal therapy and dental restorations. This approach resulted in significant clinical improvement, with no recurrence of hemoptysis and favorable findings on chest X-ray. This case highlights the intricate interplay of risk factors in the development of pulmonary actinomycosis. It underscores the effectiveness of a multidisciplinary treatment strategy combining antibiotic therapy and dental care, which improved the patient's condition and avoided unnecessary interventions such as lung resection.

摘要

全胃切除术、大量饮酒、吸烟和口腔卫生不良等综合风险因素可能促使肺放线菌病的发生。在此,我们报告一例由全胃切除术和大量饮酒引发的罕见肺放线菌病病例。该患者出现咯血和疑似肺部肿块。鉴于有全胃切除术和大量饮酒史,患者接受了影像学检查,最初提示为肺癌。虽然影像学检查最初提示为肺癌,但在首次活检显示为慢性支气管炎后,多次支气管镜检查最终确诊为肺放线菌病。该患者接受了口服阿莫西林治疗(1500毫克/天,持续六个月),同时接受了包括牙周治疗和牙齿修复在内的全面牙科护理。这种治疗方法带来了显著的临床改善,咯血未再复发,胸部X线检查结果良好。该病例突出了肺放线菌病发生过程中风险因素的复杂相互作用。它强调了联合抗生素治疗和牙科护理的多学科治疗策略的有效性,这种策略改善了患者的病情,避免了诸如肺切除等不必要的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39e0/11763416/7915b9e3011c/cureus-0016-00000076398-i01.jpg

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