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特发性高嗜酸性粒细胞综合征合并神经系统和皮肤受累的心肌炎:病例报告

Myocarditis with neurological and dermatological involvement in idiopathic Hypereosinophilic syndrome: Case report.

作者信息

Ihssane Merimi, Asmae Mrabet, Nisrine Abarkane, Habiba Bennesser Alaoui, Elouafi Noha, Ismaili Nabila

机构信息

Faculty of Medicine and Pharmacy, Mohammed Ist University, Department of Cardiology, Mohammed VI University Hospital/Mohammed I University Oujda Morocco, Oujda, Morocco.

Department of Internal Medicine, Mohammed VI University Hospital/Mohammed I University Oujda Morocco, Oujda, Morocco.

出版信息

Radiol Case Rep. 2025 Jan 4;20(3):1666-1670. doi: 10.1016/j.radcr.2024.11.091. eCollection 2025 Mar.

Abstract

Eosinophilic myocarditis (EM), irrespective of its unique etiology, is marked by varying extents of eosinophil infiltration, frequently accompanied by peripheral eosinophilia. In some instances, the etiology remains undetermined, thus classified as idiopathic hypereosinophilic syndrome. The clinical manifestations are highly variable, ranging from mild or asymptomatic presentations to acute fulminant myocarditis or chronic restrictive cardiomyopathy. We report a case of idiopathic hypereosinophilic syndrome, characterized by eosinophilic myocarditis, alongside axonal and dermatological involvement. During the follow-up period, the patient demonstrated significant clinical and echocardiographic improvement under corticotherapy and heart failure management, including normalization of eosinophil counts.

摘要

嗜酸性粒细胞性心肌炎(EM),无论其独特病因如何,其特征是嗜酸性粒细胞浸润程度各异,常伴有外周血嗜酸性粒细胞增多。在某些情况下,病因仍未明确,因此归类为特发性高嗜酸性粒细胞综合征。其临床表现高度多变,从轻度或无症状表现到急性暴发性心肌炎或慢性限制性心肌病。我们报告一例特发性高嗜酸性粒细胞综合征病例,其特征为嗜酸性粒细胞性心肌炎,同时伴有轴索性和皮肤性受累。在随访期间,患者在皮质激素治疗和心力衰竭管理下,包括嗜酸性粒细胞计数恢复正常,临床和超声心动图表现有显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81ec/11757212/d76368119950/gr1.jpg

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