Chen Kasha, Zhao Jasmine, Sasani Ali, Sabour Ryan, Cho Hannah, Bansal Riya, Shu Chang, O'Connell Ryan, Houshyar Roozbeh
Department of Radiology, University of California, Irvine, CA, USA.
Department of Pathology, University of California, Irvine, CA, USA.
Radiol Case Rep. 2025 Jan 7;20(3):1726-1735. doi: 10.1016/j.radcr.2024.12.044. eCollection 2025 Mar.
Mixed epithelial and stromal tumor (MEST) of the kidney is a rare benign neoplasm composed of both stromal and epithelial components. MEST is mainly seen in adults with a strong predilection for perimenopausal women with history of hormone replacement therapy. While MEST is generally benign, there are reported cases of malignant transformation and adverse clinical outcomes. This case series will present 7 cases of this rare renal neoplasm with emphasis on radiological imaging as an important tool in the guidance of clinical management. Considering the rarity of this tumor and its variable presentation, understanding the radiological features on multiple modalities can guide appropriate clinical and surgical management of MEST patients.
肾脏混合性上皮和间质瘤(MEST)是一种罕见的良性肿瘤,由间质和上皮成分组成。MEST主要见于成年人,尤其好发于有激素替代治疗史的围绝经期女性。虽然MEST通常为良性,但有恶变及不良临床结局的病例报道。本病例系列将展示7例这种罕见的肾脏肿瘤,重点强调放射影像学作为指导临床管理的重要工具。鉴于该肿瘤的罕见性及其表现多样,了解多种影像学检查的特征可指导MEST患者进行适当的临床和手术管理。