Subramaniam Mythily, Abdin Edimansyah, Asharani P V, Roystonn Kumarasan, Devi Fiona, Peizhi Wang, Shafie Saleha, Sagayadevan Vathsala, Jeyagurunathan Anitha, Chua Boon Yiang, Tan Bernard, Vaingankar Janhavi Ajit, Yao Fengyuan, Magadi Harish, Ma Stefan, Chow Wai Leng, McCrone Paul, Heng Derrick, Mahendran Rathi, Prince Martin, Ng Li Ling, Chong Siow Ann
Research Division, Institute of Mental Health, Singapore, Singapore.
Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Alzheimers Dement. 2025 Feb;21(2):e14485. doi: 10.1002/alz.14485. Epub 2025 Jan 27.
The study aimed to assess changes in the prevalence of dementia in Singapore over the past decade.
The Well-being of the Singapore Elderly (WiSE) 2023 and the WiSE 2013 studies were comprehensive, single-phase, cross-sectional surveys conducted among older adults aged ≥60 years in Singapore. WiSE 2023 included 2010 older adults and 1798 informants, whereas WiSE 2013 comprised 2565 older adults and 2421 informants.
The weighted prevalence of dementia based on the 10/66 Diagnostic Research Group (DRG) criteria was 8.8% (95% confidence interval [CI]: 7.3-10.7) in the WiSE 2023 study compared to 10% in the WiSE 2013 study (95% CI: 8.7-11.5). The proportion of those with undiagnosed dementia decreased significantly from 70.6% in WiSE 2013 to 51.5% in WiSE 2023 (p-value = 0.002).
A non-significant 12% reduction (95% CI: 1.1-3.5) in dementia prevalence was observed in Singapore over a decade, based on the WiSE 2013 and WiSE 2023 studies.
The prevalence of dementia decreased from 10% to 8.8% over a decade in Singapore. The prevalence varied by age group, ethnicity, employment status, and health factors. The prevalence of undiagnosed dementia decreased significantly from 70.6% to 51.5%.
本研究旨在评估新加坡过去十年中痴呆症患病率的变化。
《新加坡老年人福祉（WiSE）2023》和《WiSE 2013》研究是在新加坡≥60岁的老年人中进行的全面、单相横断面调查。《WiSE 2023》纳入了2010名老年人和1798名信息提供者，而《WiSE 2013》包括2565名老年人和2421名信息提供者。
根据10/66诊断研究组（DRG）标准，《WiSE 2023》研究中痴呆症的加权患病率为8.8%（95%置信区间[CI]：7.3-10.7），而《WiSE 2013》研究中的患病率为10%（95%CI：8.7-11.5）。未确诊痴呆症患者的比例从《WiSE 2013》中的70.6%显著下降至《WiSE 2023》中的51.5%（p值=0.002）。
根据《WiSE 2013》和《WiSE 2023》研究，新加坡在十年间痴呆症患病率出现了12%的非显著下降（95%CI：-3.5-1.1）。
新加坡的痴呆症患病率在十年间从10%降至8.8%。患病率因年龄组、种族、就业状况和健康因素而异。未确诊痴呆症的患病率从70.6%显著下降至51.5%。
