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关节周围神经组冷冻神经lysis作为终末期内科合并症患者髋部骨折姑息性非手术治疗的一种选择。 (注:“lysis”常见释义为“分解、溶解”等,这里结合语境可能是一种特定医学术语,暂时保留英文)

Pericapsular nerve group cryoneurolysis as an option for palliative nonoperative management of hip fracture in a patient with end-stage medical comorbidities.

作者信息

Endersby Ryan V W, Fifen Joanna J, Beauchemin-Turcotte Marie-Eve, Goldstein David H, Ho Esther C Y, Ip Vivian H Y

机构信息

Department of Anesthesiology, Perioperative and Pain Medicine, Alberta Health Services and Cumming School of Medicine, University of Calgary, South Health Campus, 4448 Front St. SE, Calgary, AB, T3M 1M4, Canada.

出版信息

Can J Anaesth. 2025 Feb;72(2):364-368. doi: 10.1007/s12630-024-02902-2. Epub 2025 Jan 27.

Abstract

PURPOSE

We report the use of a pericapsular nerve group (PENG) cryoneurolysis for longer-term analgesia in a patient with a hip fracture and severe medical comorbidities as an alternative to hip fracture surgery.

CLINICAL FEATURES

A frail but lucid and fully autonomous 97-yr-old female from an assisted living facility sustained a subcapital fracture of her right proximal femur following a ground level fall. She had significant comorbidities including end-stage respiratory disease. An attempt was made to proceed with a hemiarthroplasty; however, following a spinal anesthetic with 2 mL of 0.5% isobaric bupivacaine, she suffered significant respiratory compromise resulting in abortion of the surgical procedure. A multidisciplinary shared decision was made for palliative nonoperative management (P-NOM), and PENG cryoneurolysis was successfully performed. This significantly reduced the patient's pain on movement, which greatly enhanced and facilitated nursing care for the patient. She no longer required any opioid analgesia for the remainer of her stay, and residual pain was managed with regular acetaminophen. She was able to get up to standing with the help of the physiotherapist or nursing staff, who commented favourably on her improvement after cryoneurolysis. She continued to do well and was discharged to an assisted living facility seven days later.

CONCLUSION

Our case report shows that PENG cryoneurolysis can be used as an option for P-NOM in hip fracture surgery to provide significant and durable pain relief for those patients who may not be suitable for anesthesia and surgery.

摘要

目的

我们报告了在一名髋部骨折且伴有严重内科合并症的患者中使用关节囊周围神经组(PENG)冷冻神经lysis术以实现长期镇痛,作为髋部骨折手术的替代方法。

临床特征

一名来自辅助生活设施的97岁体弱但神志清醒且完全自主的女性,在平地跌倒后发生右股骨近端头下型骨折。她有包括终末期呼吸系统疾病在内的显著合并症。曾尝试进行半髋关节置换术;然而,在使用2毫升0.5%等比重布比卡因进行脊髓麻醉后,她出现了严重的呼吸功能不全,导致手术中止。经多学科共同决策,采取姑息性非手术治疗(P-NOM),并成功进行了PENG冷冻神经lysis术。这显著减轻了患者活动时的疼痛,极大地改善并便利了对患者的护理。在其住院剩余时间里,她不再需要任何阿片类镇痛药物,残余疼痛通过定期服用对乙酰氨基酚进行处理。在物理治疗师或护理人员的帮助下,她能够站立起来,他们对她冷冻神经lysis术后的改善给予了积极评价。她情况持续良好,七天后出院回到辅助生活设施。

结论

我们的病例报告表明,PENG冷冻神经lysis术可作为髋部骨折手术中P-NOM的一种选择,为那些可能不适合麻醉和手术的患者提供显著且持久的疼痛缓解。

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