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创新诊断工具助力非酒精性肝硬化患者轻微肝性脑病的筛查。

Innovative diagnostic tool aids screening for minimal hepatic encephalopathy in non-alcoholic cirrhosis patients.

作者信息

Li Ting, Li Ya-Ping

机构信息

Department of Infectious Diseases, The Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital), Xi'an 710004, Shaanxi Province, China.

出版信息

World J Hepatol. 2025 Jan 27;17(1):101420. doi: 10.4254/wjh.v17.i1.101420.

Abstract

In this editorial we comment on the article by Jiang . We focus on the EncephalApp Stroop test which is an innovative, smartphone-based tool specifically designed for screening minimal hepatic encephalopathy (MHE) in cirrhosis patients. Traditional MHE screening methods, while highly sensitive and specific, are often complex, time-consuming, and require controlled environmental conditions, limiting their widespread clinical use. The EncephalApp Stroop test simplifies the screening process, enhances diagnostic efficiency, and is applicable across diverse cultural contexts. However, the combination of additional biomarkers could further improve diagnostic accuracy. Despite its promising potential, more multicenter clinical studies are required to validate its effectiveness and applicability on a global scale.

摘要

在这篇社论中,我们对蒋的文章进行评论。我们关注的是EncephalApp斯特鲁普测试,这是一种创新的、基于智能手机的工具,专门设计用于筛查肝硬化患者的轻微肝性脑病(MHE)。传统的MHE筛查方法虽然具有高度的敏感性和特异性,但往往复杂、耗时,且需要可控的环境条件,这限制了它们在临床上的广泛应用。EncephalApp斯特鲁普测试简化了筛查过程,提高了诊断效率,并且适用于不同的文化背景。然而,结合其他生物标志物可能会进一步提高诊断准确性。尽管其潜力巨大,但仍需要更多的多中心临床研究来在全球范围内验证其有效性和适用性。

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Quality of life in patients with minimal hepatic encephalopathy.轻微肝性脑病患者的生活质量。
World J Gastroenterol. 2018 Dec 28;24(48):5446-5453. doi: 10.3748/wjg.v24.i48.5446.

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