慢性乙型肝炎病毒感染母亲所生婴儿接种疫苗后检测的时间安排。

Timing of post-vaccination tests in infants born to mothers with chronic hepatitis B virus infection.

作者信息

Emiroglu Halil Haldun, Emiroglu Melike

机构信息

Division of Pediatric Gastroenterology, Department of Pediatrics, Selcuk University Faculty of Medicine, Konya 42130, Türkiye.

Division of Pediatric Infectious Diseases, Department of Pediatrics, Selcuk University Faculty of Medicine, Konya 42130, Türkiye.

出版信息

World J Hepatol. 2025 Jan 27;17(1):101619. doi: 10.4254/wjh.v17.i1.101619.

DOI:10.4254/wjh.v17.i1.101619

PMID:39871913

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11736470/

Abstract

Immunoprophylaxis is routinely recommended for infants born to mothers with hepatitis B virus (HBV) infection within the first 12-24 hours. Detection of hepatitis B surface antibody (HBsAb) resulting from hepatitis B immunoglobulin administered at birth may be perceived as a real vaccine response. This makes it difficult to detect HBV infection. For this reason, it is recommended that infants born to hepatitis B surface antigen positive mothers and who received immunoprophylaxis at birth should have HBsAb testing when they are 9-15 months old.

摘要

对于母亲感染乙型肝炎病毒（HBV）的婴儿，通常建议在出生后的12至24小时内进行免疫预防。出生时接种乙型肝炎免疫球蛋白后产生的乙型肝炎表面抗体（HBsAb）检测结果可能会被视为真正的疫苗反应。这使得检测HBV感染变得困难。因此，建议母亲乙型肝炎表面抗原呈阳性且出生时接受过免疫预防的婴儿在9至15个月大时进行HBsAb检测。