Manna R, Ghirlanda G, Bochicchio G B, Papa G, Annese V, Greco A V, Taranto C A, Magaro M
Clin Rheumatol. 1985 Mar;4(1):93-6. doi: 10.1007/BF02032326.
In a patient with Behcet's syndrome the finding of five times the normal level of serum transaminase accompanied by weakness may be correlated to the syndrome itself. We performed needle biopsy of the liver in our patient which showed piecemeal necrosis and portal lympho-monocytic infiltration extending into the lobule. It is interesting that HLA B5 and B27 antigens were present. Simultaneous occurrence of chronic active hepatitis and Behcet's syndrome may imply the same autoimmune pathogenesis, as we suggest in this work.
在一名白塞病患者中，血清转氨酶水平是正常水平的五倍且伴有乏力，这一发现可能与该综合征本身相关。我们对该患者进行了肝脏穿刺活检，结果显示有桥接坏死以及延伸至小叶的门脉区淋巴细胞浸润。有趣的是，患者存在HLA B5和B27抗原。正如我们在这项研究中所提出的，慢性活动性肝炎与白塞病综合征的同时出现可能意味着相同的自身免疫发病机制。
