治疗策略与纵向结果的见解：NELL1 阳性膜性肾病队列的回顾性分析
Insights into Therapeutic Strategies and Longitudinal Outcomes: A Retrospective Analysis of NELL1 Positive Membranous Nephropathy Cohort.
作者信息
Singh Gurjot, Makhija Harsha, Beniwal Pankaj, Malhotra Vinay
机构信息
Department of Nephrology, Sawai Man Singh Medical College, Jaipur, India.
出版信息
Indian J Nephrol. 2025 Jan-Feb;35(1):87-90. doi: 10.25259/IJN_443_2024. Epub 2024 Oct 17.
Membranous nephropathy (MN) is a rare autoimmune disease, in which the circulating autoantibodies against antigens attack podocytes. Neural Epidermal Growth Factor like 1 (NELL1) 1-associated MN is the second most common antigen, following phospholipase A2 receptor. Complementary and alternative medicine and malignancies play a pivotal role in the development of NELL1-MN. This retrospective study describes the clinical characteristics, therapeutic strategies, and longitudinal outcomes in patients with NELL1-MN at our center.
膜性肾病（MN）是一种罕见的自身免疫性疾病，其中针对抗原的循环自身抗体攻击足细胞。神经表皮生长因子样1（NELL1）相关的MN是第二常见的抗原，仅次于磷脂酶A2受体。补充和替代医学以及恶性肿瘤在NELL1-MN的发展中起关键作用。这项回顾性研究描述了我们中心NELL1-MN患者的临床特征、治疗策略和长期预后。
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