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以肠坏疽为表现的门静脉肠系膜静脉血栓形成

Portomesenteric Venous Thrombosis Presenting as Bowel Gangrene.

作者信息

Khalifa Sania, Nichat Pramod, Gandhi Ami S, Gorhe Viraj, Patel Nishit

机构信息

General Surgery, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, IND.

General Surgery, Grant Government Medical College and JJ Group of Hospitals, Mumbai, IND.

出版信息

Cureus. 2024 Dec 26;16(12):e76410. doi: 10.7759/cureus.76410. eCollection 2024 Dec.

Abstract

Portal vein thrombosis (PVT) typically arises in patients with underlying cirrhosis, hepatobiliary malignancies, abdominal inflammatory conditions, or hematologic disorders. However, in non-cirrhotic individuals, PVT is less common and may initially present with minimal symptoms, escalating significantly if it extends to the mesenteric veins. Here, we present the case of a 37-year-old male with combined portal and mesenteric venous thrombosis, manifesting as acute intestinal obstruction. He was successfully managed with an exploratory laparotomy, resection of gangrenous bowel, and systemic anticoagulation therapy. This case highlights the critical role of early surgical intervention in preventing mortality associated with non-cirrhotic PVT.

摘要

门静脉血栓形成(PVT)通常发生在患有潜在肝硬化、肝胆恶性肿瘤、腹部炎症性疾病或血液系统疾病的患者中。然而,在非肝硬化个体中,PVT较少见,最初可能表现为轻微症状,如果扩展到肠系膜静脉则症状会显著加重。在此,我们报告一例37岁男性合并门静脉和肠系膜静脉血栓形成,表现为急性肠梗阻的病例。通过剖腹探查术、切除坏疽肠段及全身抗凝治疗,患者成功治愈。该病例强调了早期手术干预在预防非肝硬化PVT相关死亡率方面的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4166/11770161/659a3c57394e/cureus-0016-00000076410-i01.jpg

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