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Metabolomic profiling and prognostication in COVID-19 acute respiratory distress syndrome.

作者信息

Furfaro David, Che Xiaoyu, Gou Wenhao, Cummings Matthew J, Mishra Nischay, Brodie Daniel, Briese Thomas, Fiehn Oliver, Lipkin W Ian, O'Donnell Max R

机构信息

Division of Pulmonary, Critical Care, and Sleep Medicine at Beth Israel Deaconess Medical Center, MA, USA.

Center for Infection and Immunity, Columbia University Irving Medical Center and the Mailman School of Public Health, NY, USA.

出版信息

J Intensive Med. 2024 May 7;5(1):108-110. doi: 10.1016/j.jointm.2024.04.001. eCollection 2025 Jan.

DOI:10.1016/j.jointm.2024.04.001
PMID:39872829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11763573/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/11763573/91f39e554a2c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/11763573/f96ab931af38/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/11763573/91f39e554a2c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/11763573/f96ab931af38/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/11763573/91f39e554a2c/gr2.jpg

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本文引用的文献

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Marked elevations in lung and plasma ceramide in COVID-19 linked to microvascular injury.COVID-19 患者肺部和血浆神经酰胺水平显著升高与微血管损伤有关。
JCI Insight. 2023 May 22;8(10):e156104. doi: 10.1172/jci.insight.156104.
2
Lysophosphatidylcholine Alleviates Acute Lung Injury by Regulating Neutrophil Motility and Neutrophil Extracellular Trap Formation.溶血磷脂酰胆碱通过调节中性粒细胞运动和中性粒细胞胞外陷阱形成减轻急性肺损伤。
Front Cell Dev Biol. 2022 Jul 4;10:941914. doi: 10.3389/fcell.2022.941914. eCollection 2022.
3
Plasmalogen Loss in Sepsis and SARS-CoV-2 Infection.
脓毒症和新型冠状病毒肺炎感染中的缩醛磷脂损失
Front Cell Dev Biol. 2022 Jun 6;10:912880. doi: 10.3389/fcell.2022.912880. eCollection 2022.
4
Latent Class Analysis Reveals COVID-19-related Acute Respiratory Distress Syndrome Subgroups with Differential Responses to Corticosteroids.潜类分析揭示 COVID-19 相关急性呼吸窘迫综合征亚组对皮质类固醇的反应存在差异。
Am J Respir Crit Care Med. 2021 Dec 1;204(11):1274-1285. doi: 10.1164/rccm.202105-1302OC.
5
Large-Scale Multi-omic Analysis of COVID-19 Severity.大规模多组学分析 COVID-19 严重程度。
Cell Syst. 2021 Jan 20;12(1):23-40.e7. doi: 10.1016/j.cels.2020.10.003. Epub 2020 Oct 8.
6
Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study.《纽约市 COVID-19 重症成人的流行病学、临床病程和结局:一项前瞻性队列研究》
Lancet. 2020 Jun 6;395(10239):1763-1770. doi: 10.1016/S0140-6736(20)31189-2. Epub 2020 May 19.
7
ARDS Subphenotypes: Understanding a Heterogeneous Syndrome.急性呼吸窘迫综合征(ARDS)亚表型:理解一种异质性综合征。
Crit Care. 2020 Mar 24;24(1):102. doi: 10.1186/s13054-020-2778-x.
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