Carter Thomas R
Banner University of Arizona-Phoenix, 7400 N Dobson Rd, Scottsdale, AZ, 86256, U.S.A..
Curr Rev Musculoskelet Med. 2025 Apr;18(4):115-122. doi: 10.1007/s12178-025-09944-z. Epub 2025 Jan 28.
Meniscectomy alters knee function and known to be associated with an increased incidence of knee arthritis. Several methods and materials have been tried to replicate the function of a meniscus. One is a polycarbonate-urethane synthetic medial meniscus implant labeled as NUsurface. It is a non-anchored implant that is meant to replace the native meniscus. This article is intended to give an overview of the NUsurface implant and the experience to date.
The NUsurface implant is not intended to be a substitute for arthroplasty but has indications similar to meniscal allografts. It has had both prospective double armed and single armed prospective studies. Follow up at the 2-year mark has shown the implant can be successful in decreasing patients' pain and improving function. However, the reoperation rate has been high with a little over a 1/3 requiring an additional procedure and 30% requiring implant exchanged. With improved surgical technique and knowledge of contributing anatomic variables, the reoperation rate has been decreased by half. The synthetic medial meniscus implant NUsurface is able to improve the quality of life in select patients that are symptomatic after meniscectomy. The reoperation rate is of concern but it is decreasing as we refine the variables contributing to the high rate.
半月板切除术会改变膝关节功能，且已知与膝关节关节炎发病率增加有关。人们尝试了多种方法和材料来复制半月板的功能。其中一种是标记为NUsurface的聚碳酸酯 - 聚氨酯合成内侧半月板植入物。它是一种非锚定植入物，旨在替代天然半月板。本文旨在概述NUsurface植入物及迄今为止的相关经验。
NUsurface植入物并非旨在替代关节成形术，但其适应症与半月板同种异体移植相似。它进行了前瞻性双臂和单臂前瞻性研究。2年随访显示，该植入物在减轻患者疼痛和改善功能方面可能成功。然而，再次手术率一直很高，略超过三分之一的患者需要额外手术，30%的患者需要更换植入物。随着手术技术的改进以及对相关解剖变量认识的提高，再次手术率已降低一半。合成内侧半月板植入物NUsurface能够改善半月板切除术后有症状的特定患者的生活质量。再次手术率令人担忧，但随着我们对导致高再次手术率的变量进行优化，这一比率正在下降。
