Roux Julia, Bommier-Laur Domitille, Calota Mariana, Auvin Stéphane, Deiva Kumaran
Department of Pediatrics Neurology, Bicêtre Hospital, Public Assistance-Hospitals of Paris, Le Kremlin-Bicêtre, France.
Department of Pediatrics Neurology, Robert Debré Hospital, Public Assistance-Hospitals of Paris, Paris, France.
Arch Pediatr. 2025 Feb;32(2):143-146. doi: 10.1016/j.arcped.2024.11.005. Epub 2025 Jan 27.
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is a neuro-inflammatory condition affecting adults and children. The presentations vary and include acute disseminated encephalomyelitis, optic neuritis or transverse myelitis. Optic neuritis associated with anti-MOG antibodies is typically bilateral, anterior and initially severe but usually resolves quickly and completely. Here, we describe 3 children with pseudotumoural optic neuritis associated with anti-MOG antibodies and their outcome. Recognizing these unusual presentations may reduce unnecessary work-ups and improve functional prognosis by implementing rapid and adequate treatment.
髓鞘少突胶质细胞糖蛋白（MOG）抗体相关疾病（MOGAD）是一种影响成人和儿童的神经炎症性疾病。其表现多样，包括急性播散性脑脊髓炎、视神经炎或横贯性脊髓炎。与抗MOG抗体相关的视神经炎通常为双侧性、前部受累且起病时严重，但通常迅速且完全缓解。在此，我们描述3例与抗MOG抗体相关的假瘤性视神经炎患儿及其转归。认识到这些不寻常的表现可能会减少不必要的检查，并通过实施快速且充分的治疗改善功能预后。
