Violanti John M, Fekedulegn Desta, Mnatsakanova Anna, Gu Ja K, Service Samantha, Allison Penelope, Hartley Tara A
From the Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, the State University of New York, Buffalo, New York (J.M.V.), Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia (D.F., A.M., J.K.G., S.S., P.A.), and Office of the Director, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia (T.A.H.).
J Occup Environ Med. 2025 Apr 1;67(4):285-292. doi: 10.1097/JOM.0000000000003316. Epub 2025 Jan 15.
This study estimated risk of metabolic syndrome (MetSyn) and its components among police officers including differences by sex.
Police officers were examined at baseline and two follow-up examinations after 7 and 12 years. MetSyn was defined using the 2005 guidelines from the American Heart Association/National Heart, Lung, and Blood Institute. Risk for incident MetSyn and its components at follow-up exams and risk ratios in males compared to females were estimated using modified Poisson regression.
The 7- ( n = 276) and 12- ( n = 191) year incidence of MetSyn was 20.4% and 22.2%, respectively. MetSyn components with lowest and highest incidence were reduced HDL cholesterol and abdominal obesity. The 7-year risk of developing glucose intolerance was two-fold higher in males compared to females.
Longitudinal analysis of incidence of MetSyn and its components is important for understanding future cardiovascular disease morbidity and mortality.
本研究评估了警察群体中代谢综合征(MetSyn)及其各组分的风险,以及不同性别之间的差异。
对警察进行了基线检查,并在7年和12年后进行了两次随访检查。MetSyn根据美国心脏协会/国家心肺血液研究所2005年的指南进行定义。使用修正泊松回归法估计随访检查时MetSyn及其各组分的发病风险以及男性与女性相比的风险比。
MetSyn在7年(n = 276)和12年(n = 191)时的发病率分别为20.4%和22.2%。发病率最低和最高的MetSyn组分分别是高密度脂蛋白胆固醇降低和腹型肥胖。男性发生葡萄糖耐量异常的7年风险是女性的两倍。
对MetSyn及其组分发病率的纵向分析对于理解未来心血管疾病的发病率和死亡率具有重要意义。