Mitochondrial genome diversity drives heterogeneity in HCC.
作者信息
Shibata Tatsuhiro, Hoshida Yujin
机构信息
Laboratory of Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan.
Division of Cancer Genomics, National Cancer Center, Chuo-ku, Tokyo, Japan.
出版信息
Hepatology. 2025 Jul 1;82(1):12-13. doi: 10.1097/HEP.0000000000001161. Epub 2024 Nov 12.
Abstract
摘要
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本文引用的文献
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Unraveling bidirectional evolution of unstable mitochondrial DNA mutations in hepatocellular carcinoma at single-cell resolution.在单细胞分辨率下解析肝细胞癌中不稳定线粒体DNA突变的双向进化
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2
Mitochondrial metabolism: A moving target in hepatocellular carcinoma therapy.线粒体代谢：肝细胞癌治疗中一个不断变化的靶点。
J Cell Physiol. 2025 Jan;240(1):e31441. doi: 10.1002/jcp.31441. Epub 2024 Sep 26.
3
Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update.晚期肝细胞癌的系统治疗：ASCO 指南更新。
J Clin Oncol. 2024 May 20;42(15):1830-1850. doi: 10.1200/JCO.23.02745. Epub 2024 Mar 19.
4
Molecular and immune landscape of hepatocellular carcinoma to guide therapeutic decision-making.肝细胞癌的分子和免疫格局以指导治疗决策。
Hepatology. 2025 Mar 1;81(3):1038-1057. doi: 10.1097/HEP.0000000000000513. Epub 2023 Jun 12.
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Mitochondrial DNA variation and cancer.线粒体 DNA 变异与癌症。
Nat Rev Cancer. 2021 Jul;21(7):431-445. doi: 10.1038/s41568-021-00358-w. Epub 2021 May 27.
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The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease.线粒体 DNA 异质性的动态变化：对人类健康和疾病的影响。
Nat Rev Genet. 2015 Sep;16(9):530-42. doi: 10.1038/nrg3966.
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