Effects of acute physical exercise on some serum enzymes in healthy male subjects between the ages of 40 and 64 years.

The study purported to compare the effects of acute physical exercise on the serum enzymes, creatine kinase, lactate dehydrogenase, glutamic pyruvic transaminase (GPT), and glutamic oxaloacetic transaminase (GOT) in two groups of older men ranging in age from 40 to 64 years. The exercise consisted of walking on a motor driven-treadmill until the subjects reached approximately 90% of their predicted maximal heart rate. The enzymes' activity of CPK, GOT, and GPT were increased significantly in the younger group. Only GOT increased significantly in the older group. There was a correlation between the enzyme activity of GOT and GPT in both the younger and older age groups.