Tanaka Shinichi, Ohmine Takahiro, Imanaka Ryota, Maeda Takashi
Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Hiroshima, Japan.
Department of Hepatology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Hiroshima, Japan.
Ann Vasc Dis. 2025;18(1). doi: 10.3400/avd.cr.24-00107. Epub 2025 Jan 1.
Cold agglutinin disease (CAD) is a rare and autoimmune hemolytic disorder caused by the presence of cold-reacting autoantibodies against red blood cells. An abdominal aortic aneurysm (AAA) is a potentially life-threatening condition. This report describes an 83-year-old man with AAA who was diagnosed with primary CAD 9 years before undergoing AAA surgery. The patient underwent successful endovascular aortic repair. Temporary hemolytic anemia and exacerbation of jaundice were observed postoperatively despite strict temperature control. Red blood cell and haptoglobin transfusions may prevent fatal hemolytic anemia, renal disorders, embolism, and systemic complications.
冷凝集素病（CAD）是一种罕见的自身免疫性溶血性疾病，由针对红细胞的冷反应自身抗体引起。腹主动脉瘤（AAA）是一种潜在的危及生命的疾病。本报告描述了一名患有AAA的83岁男性，在接受AAA手术前9年被诊断为原发性CAD。患者接受了成功的血管内主动脉修复术。尽管严格控制体温，但术后仍观察到暂时性溶血性贫血和黄疸加重。输注红细胞和触珠蛋白可能预防致命的溶血性贫血、肾脏疾病、栓塞和全身并发症。
