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静脉输注乳酸盐治疗尿酸肾梗阻

Management of uric acid renal obstruction by intravenous lactate.

作者信息

Libert M H, Wart F

出版信息

Eur Urol. 1985;11(1):22-5. doi: 10.1159/000472443.

DOI:10.1159/000472443
PMID:3987746
Abstract

6 patients presenting with uric acid renal obstruction were managed by alkalization of urine using intravenous perfusion of 0.16 (1/6) M sodium lactate. Despite obstructive renal failure in 3 patients, rapid relief of obstruction was obtained and surgery was not necessary in any patient. Lysis of uric acid stones by urine alkalization is well documented [1, 4-12]. Intravenous infusion of 0.16 (1/6) M sodium lactate provides rapid urinary alkalization and is effective in the relief of obstruction by dissolution of uric acid calculi.

摘要

6例因尿酸导致肾梗阻的患者采用静脉输注0.16(1/6)M乳酸钠进行尿液碱化治疗。尽管3例患者出现梗阻性肾衰竭,但梗阻均迅速缓解,所有患者均无需手术。尿液碱化溶解尿酸结石已有充分文献记载[1,4 - 12]。静脉输注0.16(1/6)M乳酸钠可迅速碱化尿液,通过溶解尿酸结石有效缓解梗阻。

相似文献

1
Management of uric acid renal obstruction by intravenous lactate.静脉输注乳酸盐治疗尿酸肾梗阻
Eur Urol. 1985;11(1):22-5. doi: 10.1159/000472443.
2
Molar lactate in the management of uric acid renal obstruction.莫拉乳酸盐在尿酸肾梗阻治疗中的应用
J Urol. 1981 Jan;125(1):87-90. doi: 10.1016/s0022-5347(17)54913-7.
3
Dissolution of uric acid calculi with systemic alkalization.
J Urol. 1984 Aug;132(2):286-7. doi: 10.1016/s0022-5347(17)49598-x.
4
Chemodissolution of urinary uric acid stones by alkali therapy.碱疗法对尿酸尿路结石的化学溶解作用。
Urol Int. 1992;48(1):81-6. doi: 10.1159/000282302.
5
Management of the choked ureter in obstructive renal failure due to uric acid lithiasis.
J Urol. 1982 Aug;128(2):257-61. doi: 10.1016/s0022-5347(17)52878-5.
6
Dissolution of renal uric acid calculus with allopurinal and alkalization of urine: a case report.
J Urol. 1976 Jun;115(6):740-1. doi: 10.1016/s0022-5347(17)59358-1.
7
[The dissolution of obstructive uric acid lithiasis by intravenous perfusion of 1/6 molar lactate].
Acta Urol Belg. 1985;53(1):32-40.
8
Uric acid calculi: results of conservative treatment.尿酸结石:保守治疗结果
Urology. 1977 Dec;10(6):536-8. doi: 10.1016/0090-4295(77)90095-4.
9
Update on the pathophysiology and management of uric acid renal stones.尿酸盐肾结石的病理生理学和治疗进展。
Curr Rheumatol Rep. 2010 Apr;12(2):125-9. doi: 10.1007/s11926-010-0089-y.
10
[Dissolution of uric acid calculi].[尿酸结石的溶解]
Zhonghua Wai Ke Za Zhi. 1985 Sep;23(9):562-4, 574-5.