Management of uric acid renal obstruction by intravenous lactate.

6 patients presenting with uric acid renal obstruction were managed by alkalization of urine using intravenous perfusion of 0.16 (1/6) M sodium lactate. Despite obstructive renal failure in 3 patients, rapid relief of obstruction was obtained and surgery was not necessary in any patient. Lysis of uric acid stones by urine alkalization is well documented [1, 4-12]. Intravenous infusion of 0.16 (1/6) M sodium lactate provides rapid urinary alkalization and is effective in the relief of obstruction by dissolution of uric acid calculi.