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巩膜下巩膜切除术成功治疗双侧脉络膜骨瘤继发浆液性视网膜脱离:一例报告

Serous retinal detachment secondary to bilateral choroidal osteoma successfully treated with subscleral sclerectomy: A case report.

作者信息

Fujimoto Satoko, Maruyama Kazuichi, Shunto Takuya, Nishida Kohji

机构信息

Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Department of Vision Informatics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

出版信息

Am J Ophthalmol Case Rep. 2025 Jan 7;37:102249. doi: 10.1016/j.ajoc.2025.102249. eCollection 2025 Mar.

Abstract

PURPOSE

To report a case of bilateral choroidal osteoma successfully treated with subscleral sclerectomy for secondary serous retinal detachment (SRD).

OBSERVATIONS

A 52-year-old Japanese woman first diagnosed with Vogt-Koyanagi-Harada disease and treated with steroids for 9 years was referred to our clinic. SRD in both eyes recurred frequently and was uncontrolled with adalimumab subcutaneous injections and oral cyclosporine, in addition to steroids. A yellowish-to-orange, slightly elevated subretinal lesion was observed superior to the macular and inferotemporal regions of the right eye and superior to the macular and temporal regions of the left eye without any inflammation. Swept-source optical coherence tomography (OCT) revealed SRD in the fovea and a mass under the retinal pigment epithelium (RPE) in the macular area of both eyes. Indocyanine green angiography (ICGA) demonstrated hypocyanescence corresponding to the mass area under the RPE, with dilation of the dominant vortex veins. Ultrasonography revealed a hyperechogenic mass in the posterior wall of both eyes with deeper acoustic shadows, and computed tomography (CT) detected calcifications in the posterior wall of both eyes. A bilateral choroidal osteoma was diagnosed, and the superior SRD of her left eye increased toward the fovea without any evidence of choroidal neovascularization during follow-up. Therefore, subscleral sclerectomy (4 × 4 mm sclerectomy under the scleral flap) was performed at three sites at the equators in the upper temporal, upper nasal, and lower temporal quadrants of her left eye. Immediately after surgery, SRD resolved dramatically. As the foveal SRD of her right eye also increased after two months, the same surgery was performed, and it worked successfully.

CONCLUSIONS AND IMPORTANCE

Choroidal osteoma can cause severe SRD that cannot be controlled with medication. Although further studies are needed, subscleral sclerectomy may be an effective treatment for the resolution of subretinal fluid secondary to choroidal osteoma by improving choroidal circulation congestion.

摘要

目的

报告1例双侧脉络膜骨瘤继发浆液性视网膜脱离(SRD),经巩膜下巩膜切除术成功治疗的病例。

观察结果

一名52岁日本女性,最初被诊断为Vogt-小柳-原田病,并接受了9年的类固醇治疗,后来转诊至我院。双眼SRD频繁复发,除类固醇外,阿达木单抗皮下注射和口服环孢素均无法控制病情。在右眼黄斑上方和颞下区域以及左眼黄斑上方和颞侧区域观察到一个黄橙色、略隆起的视网膜下病变,无任何炎症。扫频光学相干断层扫描(OCT)显示双眼黄斑中心凹存在SRD,黄斑区视网膜色素上皮(RPE)下有肿物。吲哚菁绿血管造影(ICGA)显示与RPE下肿物区域对应的低荧光,伴有优势涡静脉扩张。超声检查显示双眼后壁有高回声肿物,伴有更深的声影,计算机断层扫描(CT)检测到双眼后壁有钙化。诊断为双侧脉络膜骨瘤,随访期间左眼上方SRD向黄斑中心凹进展,未发现脉络膜新生血管形成的证据。因此,在左眼颞上、鼻上和颞下象限赤道处的三个部位进行了巩膜下巩膜切除术(在巩膜瓣下切除4×4mm巩膜)。术后SRD立即显著消退。两个月后右眼黄斑中心凹SRD也加重,遂进行了相同手术,手术成功。

结论与意义

脉络膜骨瘤可导致严重的SRD,药物治疗无法控制。尽管需要进一步研究,但巩膜下巩膜切除术可能是通过改善脉络膜循环充血来解决脉络膜骨瘤继发视网膜下液的有效治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4155/11773265/4e36b07bc195/gr1.jpg

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